Direct observation of heterogeneous chemistry in the atmosphere

…, DS Gross, LS Hughes, JO Allen, BD Morrical… - Science, 1998 - science.org
The heterogeneous replacement of chloride by nitrate in individual sea-salt particles was
monitored continuously over time in the troposphere with the use of aerosol time-of-flight mass …

Evolution of atmospheric particles along trajectories crossing the Los Angeles basin

…, DY Liu, DP Fergenson, BD Morrical… - … science & technology, 2000 - ACS Publications
Trajectory analysis shows that the air masses arriving at Riverside, CA, on the afternoons of
September 24 and 25, 1996, previously passed near air monitoring sites at Santa Catalina …

Particle detection efficiencies of aerosol time of flight mass spectrometers under ambient sampling conditions

…, EE Gard, LS Hughes, BD Morrical… - Environmental …, 2000 - ACS Publications
Aerosol time-of-flight mass spectrometers (ATOFMS) measure the size and chemical
composition of single aerosol particles. To date, these instruments have provided qualitative …

Investigations on the mechanism of magnesium stearate to modify aerosol performance in dry powder inhaled formulations

MW Jetzer, M Schneider, BD Morrical… - Journal of pharmaceutical …, 2018 - Elsevier
The potential of the force control agent magnesium stearate (MgSt) to enhance the aerosol
performance of lactose-based dry powder inhaled (DPI) formulations was investigated in this …

Size and composition distribution of atmospheric particles in Southern California

…, EE Gard, ME Gälli, BD Morrical… - … science & technology, 1999 - ACS Publications
Continuous measurements of single particle size and chemical composition in the atmosphere
are made using aerosol time-of-flight mass spectrometers (ATOFMS) operated alongside …

A field-based approach for determining ATOFMS instrument sensitivities to ammonium and nitrate

PV Bhave, JO Allen, BD Morrical… - … science & technology, 2002 - ACS Publications
Aerosol time-of-flight mass spectrometry (ATOFMS) instruments measure the size and
chemical composition of individual particles in real-time. ATOFMS chemical composition …

Probing the particulate microstructure of the aerodynamic particle size distribution of dry powder inhaler combination products

MW Jetzer, BD Morrical, M Schneider, S Edge… - International journal of …, 2018 - Elsevier
The in-vitro aerosol performance of two combination dry powder inhaler (DPI) products,
Foster ® NEXThaler ® and Seretide ® Diskus ® were investigated with single particle aerosol …

Leak testing in parenteral packaging: establishment of direct correlation between helium leak rate measurements and microbial ingress for two different leak types

BD Morrical, M Goverde, J Grausse… - PDA Journal of …, 2007 - journal.pda.org
A direct test method using helium leak detection was developed to determine microbial
ingress in parenteral vial/rubber closure systems. The purpose of this study was to establish a …

Particle interactions of fluticasone propionate and salmeterol xinafoate detected with single particle aerosol mass spectrometry (SPAMS)

MW Jetzer, BD Morrical, DP Fergenson… - International journal of …, 2017 - Elsevier
Particle co-associations between the active pharmaceutical ingredients fluticasone propionate
and salmeterol xinafoate were examined in dry powder inhaled (DPI) and metered dose …

The on-line analysis of aerosol-delivered pharmaceuticals via single particle aerosol mass spectrometry

BD Morrical, M Balaxi, D Fergenson - International journal of pharmaceutics, 2015 - Elsevier
The use of single particle aerosol mass spectrometry (SPAMS) was evaluated for the analysis
of inhaled pharmaceuticals to determine the mass distribution of the individual active …