The 17q23 amplicon and breast cancer
CS Sinclair, M Rowley, A Naderi, FJ Couch - Breast cancer research and …, 2003 - Springer
A novel region of amplification in breast tumors was recently identified on chromosome
17q23. Extensive mapping of the amplicon by Southern blotting and fluorescence in situ …
17q23. Extensive mapping of the amplicon by Southern blotting and fluorescence in situ …
Comparative genomic sequence analysis and isolation of human and mouse alternative EGFR transcripts encoding truncated receptor isoforms
…, GD Eley, KE Strunk, AJ Danielsen, CS Sinclair… - Genomics, 2001 - Elsevier
This study presents the annotated genomic sequence and exon–intron organization of the
human and mouse epidermal growth factor receptor (EGFR) genes located on chromosomes …
human and mouse epidermal growth factor receptor (EGFR) genes located on chromosomes …
Discrimination of Cricotopus species (Diptera: Chironomidae) by DNA barcoding
CS Sinclair, SE Gresens - Bulletin of entomological research, 2008 - cambridge.org
Chironomids (Diptera) typically comprise the most abundant group of macroinvertebrates
collected in water quality surveys. Species in the genus Cricotopus display a wide range of …
collected in water quality surveys. Species in the genus Cricotopus display a wide range of …
TBX2 Is Preferentially Amplified in BRCA1- and BRCA2-related Breast Tumors
CS Sinclair, C Adem, A Naderi, CL Soderberg… - Cancer research, 2002 - AACR
The chromosome 17q23 region is frequently amplified in breast tumors. Gain of the region is
present in 50% of BRCA1-associated breast tumors and 87% of BRCA2-associated breast …
present in 50% of BRCA1-associated breast tumors and 87% of BRCA2-associated breast …
17q23 Amplifications in Breast Cancer Involve the PAT1, RAD51C, PS6K, and SIGMA1B Genes
GJ Wu, CS Sinclair, J Paape, JN Ingle, PC Roche… - Cancer research, 2000 - AACR
Amplification of the 17q23 region occurs frequently in breast tumors. To characterize the
structure of 17q23 amplicons and to identify oncogene targets associated with this alteration, we …
structure of 17q23 amplicons and to identify oncogene targets associated with this alteration, we …
A basidiomycete isolated from the skeleton of Pocillopora damicornis (Scleractinia) selectively stimulates short-term survival of coral skeletogenic cells
IJ Domart-Coulon, CS Sinclair, RT Hill, S Tambutté… - Marine Biology, 2004 - Springer
Endolithic fungi bore through the extracellular calcium carbonate skeleton of reef-building
scleractinian corals, both healthy and dead, and effect net erosion of coral reefs. Potential …
scleractinian corals, both healthy and dead, and effect net erosion of coral reefs. Potential …
Cryptic male mate choice for high-quality females reduces male postcopulatory success in future matings
OE Anastasio, CS Sinclair, A Pischedda - Evolution, 2023 - academic.oup.com
Cryptic male mate choice occurs when males differentially allocate resources to females
during or after copulation. When male resources are limited, males may benefit by strategically …
during or after copulation. When male resources are limited, males may benefit by strategically …
BRCA1 and BRCA2 Have a Limited Role in Familial Prostate Cancer
CS Sinclair, R Berry, D Schaid, SN Thibodeau… - Cancer research, 2000 - AACR
Epidemiological studies have suggested that the breast cancer susceptibility genes, BRCA1
and BRCA2,may be involved in the development of prostate cancer. Several studies have …
and BRCA2,may be involved in the development of prostate cancer. Several studies have …
ERBB2, TBX2, RPS6KB1, and MYC alterations in breast tissues of BRCA1 and BRCA2 mutation carriers
…, C Reynolds, JM Slezak, CS Sinclair… - Genes …, 2004 - Wiley Online Library
Breast cancer risk is greatly increased in women who carry mutations in the BRCA1 or BRCA2
genes. Because breast cancer initiation is different between BRCA1/2 mutation carriers …
genes. Because breast cancer initiation is different between BRCA1/2 mutation carriers …
Characterization of the telomere regions of scleractinian coral, Acropora surculosa
CS Sinclair, RH Richmond, GK Ostrander - Genetica, 2007 - Springer
Terminal ends of vertebrate chromosomes are protected by tandem repeats of the sequence
(TTAGGG). First thought to be vertebrate specific, (TTAGGG) n has recently been identified …
(TTAGGG). First thought to be vertebrate specific, (TTAGGG) n has recently been identified …