The Human Microbiome Project (HMP), funded as an initiative of the NIH Roadmap for
Biomedical Research ( http://nihroadmap.nih.gov ), is a multi-component community resource. …

It is well established that autism spectrum disorders (ASD) have a strong genetic component;
however, for at least 70% of cases, the underlying genetic cause is unknown 1 . Under the …

Schizophrenia is a devastating neurodevelopmental disorder whose genetic influences remain
elusive. We hypothesize that individually rare structural variants contribute to the illness. …

Background The relative efficacy and safety of intravitreous aflibercept, bevacizumab, and
ranibizumab in the treatment of diabetic macular edema are unknown. Methods At 89 clinical …

To understand the genetic heterogeneity underlying developmental delay, we compared
copy number variants (CNVs) in 15,767 children with intellectual disability and various …

Evidence for the etiology of autism spectrum disorders (ASDs) has consistently pointed to a
strong genetic component complicated by substantial locus heterogeneity 1 , 2 . We …

Here the Human Pangenome Reference Consortium presents a first draft of the human
pangenome reference. The pangenome contains 47 phased, diploid assemblies from a cohort of …

One of the most basic concerns in the writings of Noam Chomsky, beginning in Syntactic
Structures and extending through his recent work, has been to draw attention to the profundity …

We cloned and analyzed the integrated human papillomavirus type 16 (HPV-16) genomes
that are present in the human cervical carcinoma cell lines SiHa and CaSki. The single HPV-…

Background To reduce treatment burden and optimise patient outcomes in diabetic macular
oedema, we present 1-year results from two phase 3 trials of faricimab, a novel angiopoietin-…