Numerous biological processes involve the recognition of a specific pattern of binding sites
on a target protein or surface. Although ligands displayed by disordered scaffolds form …

DNA separation is important for numerous applications in biotechnology and medicine.
Efforts to improve DNA separation in microdevices have led to advances in capillary …

Most biomolecules, owing to their marginal stability in liquid state, susceptibility to microbial
growth, and tendency to foam upon storage/shipment in the liquid state, often require an …

We demonstrate that the stability of adsorbed proteins can be enhanced by controlling the
heterogeneity of the surfaceby creating raftlike domains in a soft liposomal membrane. …

Continual increase in the yields of purified proteins due to increased process efficiencies is
steadily increasing the need for improvements in safe and efficient storage methods, and the …

We describe the influence of membrane heterogeneity on the adsorption and diffusion of DNA.
Cellular membranes are believed to contain domains (lipid rafts) that influence processes …

Recent studies on the diffusion of adsorbed polymers such as DNA on supported lipid
bilayers have suggested that such strongly adsorbed polymers can be treated similarly to a …

A new type of lamellae-like particles was observed in protein based liquid therapeutic protein
drug product (DP) packaged in standard (STD) and delamination controlled (DC) Type IB …

A previously unreported particle type was observed during routine visual vial inspection of a
liquid drug product and suspected to be the result of vial delamination. Delamination is the …

This manuscript describes the influence of chain length on the diffusion and electrophoresis
of single stranded DNA (ssDNA) adsorbed on heterogeneous cationic supported lipid …