Modern mass spectrometry-the instrumentation and applications in diverse fields Mass
spectrometry has played a pivotal role in a variety of scientific disciplines. Today it is an integral …

Serum albumin is the principal transporter of fatty acids that are otherwise insoluble in
circulating plasma. While the crystal structure of human serum albumin (HSA) as well as its …

A family of five long-chain fatty acid carboxamides has been identified and semi-quantified
in human plasma by GC-MS. One saturated and four unsaturated amides were found. Luteal …

A method based upon immobilized metal ion affinity chromatography (IMAC) is described
for purification of phosphopeptides from the crude preparations of solid-phase peptide …

The synthesis of 11 peptides, ranging in composition from 9 to 17 amino acid residues, by
solid-phase methodology was accomplished with the purpose of studying how the amphiphilic …

To perform its biochemical functions, a protein usually folds into a well defined, highly ordered
structure. Subtle changes in conformation are frequently used in nature to modulate or …

Mass spectrometry with chemical cross-linking was used to probe the conformational changes
of HSA (human serum albumin) in solution on interaction with monounsaturated OA (oleic …

The stomach is stimulated by an enterooxyntin factor in a delayed response to feeding,
resulting in an increase in both gastric acid and pepsinogen secretion. We have previously …

In an attempt to find clinically useful modulators of multidrug resistance (MDR), a series of
19 N 10 -substituted-2-methoxyacridone analogues has been synthesized. 2-…

Although teniposide (VM26) and etoposide (VP16) are eliminated mostly by nonrenal
mechanisms, their cytochrome P450 metabolism in humans has not been reported. Our objective …