The degradation of some proto-oncogene and lymphokine mRNAs is controlled in part by an
AU-rich element (ARE) in the 3′ untranslated region. It was shown previously (G. Brewer, …

All nuclear-encoded mRNAs contain a 5′ cap structure (m 7 GpppN, where N is any nucleotide),
which is recognized by the eukaryotic translation initiation factor 4E (eIF4E) subunit of …

Long-lasting synaptic plasticity and memory requires mRNA translation, yet little is known
as to how this process is regulated. To explore the role that the translation repressor 4E-BP2 …

The steady-state levels of many mRNAs are determined in part by their turnover rates. Turnover
rates, in turn, are usually controlled by proteins that bindcis-acting sequence elements in …

Rapid degradation of many labile mRNAs is regulated in part by an A+U-rich element (ARE)
in their 3′-untranslated regions. Extensive mutational analyses of various AREs have …

The eukaryotic mRNA 3′ poly(A) tail acts synergistically with the 5′ cap structure to
enhance translation. This effect is mediated by a bridging complex, composed of the poly(A) …

In comparison with other macaque spe cies, knowledge regarding the macaques of Sulawesi
(previously Celebes) is scarce, espe cially concerning behavioural patterns. This is an odd …

Flow cytometry was partnered with a nonfluorescent reporter protein for rapid, early stage
identification of clones producing high levels of a therapeutic protein. A cell surface protein, not …

mRNA turnover is an important regulatory component of gene expression and is significantly
influenced by ribonucleoprotein (RNP) complexes which form on the mRNA. Studies of …

In both cell culture based model systems and in the failing human heart, β-adrenergic
receptors (β-AR) undergo agonist-mediated down-regulation. This decrease correlates closely …