Investigation of enzyme kinetics using quench− flow techniques with MALDI-TOF mass spectrometry

CT Houston, WP Taylor, TS Widlanski… - Analytical …, 2000 - ACS Publications
Matrix-assisted laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry is
combined off-line with rapid chemical quench−flow methods to investigate the pre-steady-…

Toward a simple, expedient, and complete analysis of human hemoglobin by MALDI-TOFMS

CT Houston, JP Reilly - Analytical chemistry, 1999 - ACS Publications
MALDI mass spectrometry is explored as a method for hemoglobin characterization. To
simplify and expedite the analysis, hemoglobin is obtained without purification directly from …

Principles for management of extractables and leachables in ophthalmic drug products

CT Houston, AD Rodrigues, BB Smith… - PDA Journal of …, 2022 - journal.pda.org
Ophthalmic solutions and suspensions have long been classified into a high-risk category
with respect to concerns over extractables and leachables (E&L), though specific guidance on …

Rapid analysis of hemoglobin from whole human blood by matrix‐assisted laser desorption/ionization time‐of‐flight mass spectrometry

CT Houston, JP Reilly - Rapid communications in mass …, 1997 - Wiley Online Library
Matrix‐assisted laser desorption time‐of‐flight mass spectrometry (MALDI‐TOFMS) is applied
to the analysis of whole human blood. No separation or purification steps are required to …

Photoionization studies of chromophore-labeled amino acids and peptides

CT Houston, JP Reilly - The Journal of Physical Chemistry A, 2000 - ACS Publications
The photoionization characteristics of a naphthol chromophore covalently tethered to a few
different amino acids and small peptides are investigated. To isolate the chromophore from …

[BOOK][B] Analysis of modified proteins by matrix-assisted laser desorption/ionization time-of-flight mass spectrometry

CT Houston - 1999 - search.proquest.com
INFORMATION TO USERS Page 1 INFORMATION TO USERS This manuscript has been
reproduced from the microfilm master. UMI films the text directly from the original or copy …

Adiponectin cardioprotection after myocardial ischemia/reperfusion involves the reduction of oxidative/nitrative stress

L Tao, E Gao, X Jiao, Y Yuan, S Li, TA Christopher… - Circulation, 2007 - Am Heart Assoc
Background— Several clinical studies have demonstrated that levels of adiponectin are
significantly reduced in patients with type 2 diabetes and that adiponectin levels are inversely …

[CITATION][C] Matrix‐assisted Laser Desorption/Ionization Time‐of‐flight Mass Spectrometry as a Tool to Probe the Reactions of trans‐Hex‐2‐enal with Proteins

CT Houston, AG Baker, MV Novotny… - Journal of mass …, 1997 - Wiley Online Library
Since the 1970s, extensive study has been devoted to the reactions of proteins with carbonyl
compounds. 1 Under conditions of oxidative stress, the presence of peroxides in the body …

Macrophages in ischemic heart failure: Yesterday, today, and tomorrow

…, J Huang, J Zhao, H Kilby, TA Christopher… - Cardiology …, 2021 - mednexus.org
With continually improving reperfusion strategies and patient care, the overall mortality of
acute myocardial infarction (AMI) has been significantly reduced during the past two decades. …

Early predictors of neurodevelopmental outcome in symptomatic congenital cytomegalovirus infection

…, Houston Congenital CMV Longitudinal Study … - The Journal of …, 2001 - Elsevier
Objective: To determine the ability of neonatal clinical, audiologic, and computed
tomography (CT) findings to predict long-term neurodevelopmental outcome in children with …