[HTML][HTML] CRISPRi-mediated metabolic engineering of E. coli for O-methylated anthocyanin production

BF Cress, QD Leitz, DC Kim, TD Amore, JY Suzuki… - Microbial cell …, 2017 - Springer
Background Anthocyanins are a class of brightly colored, glycosylated flavonoid pigments
that imbue their flower and fruit host tissues with hues of predominantly red, orange, purple, …

Cysteinyl leukotrienes regulate Th2 cell-dependent pulmonary inflammation

DC Kim, FI Hsu, NA Barrett, DS Friend… - The Journal of …, 2006 - journals.aai.org
The Th2 cell-dependent inflammatory response is a central component of asthma, and the
ways in which it is regulated is a critical question. The cysteinyl leukotrienes (cys-LTs) are 5-…

Hydrolysis of polysorbate 20 and 80 by a range of carboxylester hydrolases

AC McShan, P Kei, JA Ji, DC Kim… - PDA journal of …, 2016 - journal.pda.org
Degradation of the surfactant polysorbate (PS) by enzyme impurities has been previously
suggested as a mechanism for the formation of visible and subvisible particles that affect …

Anatomy of the heart at multidetector CT: what the radiologist needs to know

JP O'Brien, MB Srichai, EM Hecht, DC Kim… - Radiographics, 2007 - pubs.rsna.org
Continued improvements in multidetector computed tomographic (CT) scanners have made
cardiac CT an important clinical tool that is revolutionizing cardiac imaging. Multidetector CT …

Midshaft clavicle fractures: a critical review

JM Burnham, DC Kim, S Kamineni - Orthopedics, 2016 - journals.healio.com
The clavicle is the most commonly broken bone in the human body, accounting for up to 5%
to 10% of all fractures seen in hospital emergency admissions. Fractures of the middle third, …

Rapid generation of CRISPR/dCas9-regulated, orthogonally repressible hybrid T7-lac promoters for modular, tuneable control of metabolic pathway fluxes in …

BF Cress, JA Jones, DC Kim, QD Leitz… - Nucleic acids …, 2016 - academic.oup.com
Robust gene circuit construction requires use of promoters exhibiting low crosstalk.
Orthogonal promoters have been engineered utilizing an assortment of natural and synthetic …

Endothelin-1 as a putative modulator of erectile dysfunction: I. Characteristics of contraction of isolated corporal tissue strips

GJ Christ, SE Lerner, DC Kim, A Melman - The Journal of urology, 1995 - auajournals.org
Normal erectile physiology is heavily dependent on a delicate balance between the effects
of endogenous vasoconstricting and vasorelaxing hormones on the tone of the corporal …

[HTML][HTML] Contrasting pediatric and adult methicillin-resistant Staphylococcus aureus isolates

…, S Boyle-Vavra, MA Hostetler, DC Kim… - Emerging infectious …, 2006 - ncbi.nlm.nih.gov
We performed a prospective study of all inpatient and outpatient methicillin-resistant
Staphylococcus aureus (MRSA) isolates identified at the University of Chicago Hospitals from …

Niraparib in patients with metastatic castration-resistant prostate cancer and DNA repair gene defects (GALAHAD): a multicentre, open-label, phase 2 trial

…, T Gil, E Seront, C Vulsteke, C Kussumoto… - The Lancet …, 2022 - thelancet.com
Background Metastatic castration-resistant prostate cancers are enriched for DNA repair
gene defects (DRDs) that can be susceptible to synthetic lethality through inhibition of PARP …

Dietary fiber and probiotics influence the gut microbiome and melanoma immunotherapy response

…, JP Allison, L Cohen, G Trinchieri, CR Daniel… - Science, 2021 - science.org
Gut bacteria modulate the response to immune checkpoint blockade (ICB) treatment in cancer,
but the effect of diet and supplements on this interaction is not well studied. We assessed …