Rapid technological advances have significantly improved the capability, versatility, and
robustness of mass spectrometers which has led to them playing a central role in the …

A novel strategy for rapid chiral method development has been implemented using sample
pooling and supercritical fluid chromatography–mass spectrometry (SFC–MS) on four chiral …

The magnitude of surface enhancement from thin metal films is known to be critically
dependent on film morphol-ogy. In orderto establish the best methodology for generating …

Fluorescence correlation spectroscopy of individual Rhodamine 6G (R6G) molecules
immobilized on a silica surface is performed in air at room temperature using confocal laser …

A hydrophilic interaction liquid chromatography (HILIC) method was developed for the
analysis of very polar and basic 4-(aminomethyl)pyridine (4-AMP) and its related compounds. …

A novel application of the TMSN 3 modified Ugi 4-component reaction is disclosed for the
solution phase synthesis of fused azepine-tetrazole libraries. The reaction of a N-Boc-α-amino …

… Author links open overlay panel Laura E Blue , Xiaoyan Guan , Marisa K Joubert , Scott T
Kuhns , Stephanie Moore , David J Semin , Mats Wikström , Jette Wypych , Chetan T Goudar …

A flow cytometric, single molecule approach to DNA sequencing is described. A single,
fluorescently labeled DNA fragment is suspended in a flow stream. An exonuclease is added to …

Palladium (Pd) is extensively used in pharmaceutical small molecule drug substance
processes, however it must be removed prior to release of the active pharmaceutical ingredient (…

A novel approach to high‐throughput logP measurement based on liquid chromatography/ultraviolet/mass
spectrometry (LC/UV/MS) is proposed. The logP value is determined by …