The Syntex adjuvant formulation (SAP) containing [thr 1 ]-muramyldipeptide in an oil-in-water
emulsion has proven to be an effective adjuvant eliciting both cell-mediated and humoral …

In vitro rabbit corneal studies utilizing ketorolac tromethamine were designed to 1) determine
its permeability at different pH levels; 2) study the effects of two commonly used ophthalmic …

The hemolytic potential for a series of intravenous solutions was determined by an in vitro
testing procedure; the solutions were subsequently administered intravenously to rats and …

This chapter contains a summary of the development of a very effective adjuvant that
contains a muramyl dipeptide (MDP) analogue (threonyl-MDP, temurtide) in an oil-inwater …

A liposome system was developed which demonstrates suitability as an intravenous drug
carrier for a lipophilic drug compound (RS-93522, a dihydropyridine CA 2+ channel blocker). …

An efficacious vaccine adjuvant which elicits both cell-mediated immunity (CMI) and
humoral immune response was developed using [thr 1 -Muramyldipeptide (MDP) in an oil-in-water …

The effects of temperature and mechanical shear on the microcrystalline structure of
petrolatum are examined; syneresis determinations and rheological methods are utilized as …

The reduction in conductivity seen between a buffer solution and a liposome preparation in
that buffer was evaluated as a means of measuring liposome capture volume. Using DOPC …

In vitro rabbit corneal penetration studies were designed to determine the effect tobramycin (an
antibiotic) has on the diffusion of ketorolac tromethamine (a nonsteroidal anti-…

The Syntex adjuvant formulation (SAF) is an effective adjuvant composed of a muramyl
dipeptide derivative (threonyl-MDP) in an oil-in-water (o/w) emulsion vehicle. Threonyl-MDP (N-…