Echinacea purpurea L. is a medicinal plant originally from North America. It has become a
commonly used herbal medicine worldwide because it contains various biologically active …

Jiuzhai Valley National Park in the Aba Tibetan and Qiang Autonomous Prefecture of northern
Sichuan, China, is well renowned both at home and abroad as “World Natural Heritage,” “…

Cichoric acid extract (CAE) from Echinacea purpurea L. was used to investigate the anti-arthritic
effect by using collagen-induced arthritis (CIA) rat model. The hind paw swelling volume …

Antibody aggregate is a common issue in therapeutic antibodies, which may compromise
product efficacy and cause adverse effects. Antibody aggregate level is normally controlled in …

Typhoons have inflicted significant damage and loss of life to China, a large number of
typhoon–rainstorm–debris flow–tunnel accidents occur in the southeastern coastal areas each …

Efficient purification of protein biopharmaceuticals from transgenic plants is a major challenge,
primarily due to low target protein expression levels, and high impurity content in the feed …

N-terminus-specific PEGylation was used to produce mono-PEGylated lysozyme. However,
some di- and tri-PEGylated proteins were also produced due to side chain reaction. The …

Depth filtration‐based harvesting is widely used in mAb manufacturing to remove cell and
process‐related impurities. However, it has not been studied on control of product‐related …

Transgenic plants offer a promising system for large-scale production of therapeutic proteins
such as monoclonal antibodies (mAbs). This paper describes a membrane-based process …

Production of therapeutic monoclonal antibodies using genetically modified plants may
provide low cost, high scalability and product safety; however, antibody purification from plants …