The pharmacokinetics of theophylline was studied in 6 normal, nonsmoking, adult male
volunteers. A constant‐rate intravenous infusion of 3.84 to 4.98 mglkg oftheophylline (as the …

The application of a differential scanning calorimetric (DSC) method versus an isothermal
stress (IS) method, which utilizes HPLC analysis of simulated wet granulations stored for two …

Purpose.Dermal application of immunosuppressants can be an effective means of achieving
site-specific immunosuppression (SITE) on skin allografts in burn wound management and …

Objective To determine the efficacy of concurrent preoperative cisplatin chemotherapy and
radiotherapy (CT/RT) for patients with advanced head and neck cancer and cervical …

Several aliphatic acids were evaluated as solubilizers for haloperidol in eight oils representative
of oils employed as depot, im injection vehicles. The six acids which were adequately …

The cellular mechanisms by which topical cyclosporine A (tCsA) induces site-specific
immunosuppression were investigated. Experiments were designed to elucidate how cyclosporine …

The solubilization of zomepirac, a non-narcotic analgesic, by tromethamine and related bases
is described. Solubilization is affected by a micellar mechanism as demonstrated by the …

The ability of multiple oblique illumination (MOI) and high-definition microscopy (Edge R-400
3-D microscope) to improve resolution of cellular detail in the evaluation of …

Methods: Seventy-one patients requiring operative intervention for suspected acute
appendicitis were prospectively compared. Thirty-seven patients underwent laparoscopic …

During a study of the pharmacokinetics of theophylline using GLC analysis, unexpectedly
high values occurred in a random manner. The cause of these abnormal values was …