Determining Maximum Allowable Rubber Stopper Displacement for Container Closure Integrity (CCI)

…, S Joerg, HC Mahler, F Riesen, G Roidl… - PDA Journal of …, 2020 - journal.pda.org
Sterile pharmaceuticals require they be developed and manufactured using suitable
container closure systems to maintain sterility until product opening. Characterizing container …

[HTML][HTML] Discontinuation versus continuation of renin-angiotensin-system inhibitors in COVID-19 (ACEI-COVID): a prospective, parallel group, randomised, controlled …

…, C Wendtner, F Wenner, D Wimmert-Roidl… - The Lancet …, 2021 - thelancet.com
Background SARS-CoV-2 entry in human cells depends on angiotensin-converting enzyme
2, which can be upregulated by inhibitors of the renin–angiotensin system (RAS). We aimed …

[HTML][HTML] An In Vitro Approach to Model EMT in Breast Cancer

L Isert, A Mehta, G Loiudice, A Oliva, A Roidl… - International Journal of …, 2023 - mdpi.com
During the progression from ductal carcinoma in situ (DCIS) to invasive breast cancer (IBC),
cells must overcome the physically restraining basement membrane (BM), which …

An Interactive Modelling Environment for Designing Warehouse Layouts Based on ASP

…, G Kern-Isberner, P Kaiser, M Roidl - The International …, 2023 - journals.flvc.org
In this paper, we apply answer set programming (ASP) to the task of planning warehouse
layouts within the logistical domain. Warehouse layout planners have to take into account a …

Hybrid Production: Enabled By Controlling The Output Sequence Of A Matrix Production Using Answer Set Programming

P Kaiser, A Thevapalan, C Reining, M Roidl… - Procedia CIRP, 2022 - Elsevier
Combining a line production with a matrix production into a hybrid production is a vivid field
of research to cope with the challenges of mass personalization. Nevertheless, to implement …

Epidermal Growth Factor Receptor Signal Trans-Activation

S Hart, A Gschwind, A Roidl, A Ullrich - … Probes in Biology: Science at the …, 2003 - Springer
Coordination of complex cell functions is achieved by the regulated information transfer along
linear signalling pathways. It has become apparent, however, that these linear pathways …

Towards Finding Optimal Solutions For Constrained Warehouse Layouts Using Answer Set Programming

P Kaiser, A Thevapalan, M Roidl… - ESSN: 2701 …, 2023 - repo.uni-hannover.de
A minimum requirement of feasible order picking layouts is the accessibility of every storage
location. Obeying only this requirement typically leads to a vast amount of different layouts …

Innovations in model-based software and systems engineering

K Hölldobler, J Michael, JO Ringert, B Rumpe… - 2019 - figshare.le.ac.uk
Engineering software and software intensive systems has become increasingly complex
over the last decades. In the ongoing digitalization of all aspects of our lives in almost every …

Sequential and switchable patterning for studying cellular processes under spatiotemporal control

T Zisis, J Schwarz, M Balles, M Kretschmer… - … Applied Materials & …, 2021 - ACS Publications
Attachment of adhesive molecules on cell culture surfaces to restrict cell adhesion to defined
areas and shapes has been vital for the progress of in vitro research. In currently existing …

Geometry adaptation of protrusion and polarity dynamics in confined cell migration

DB Brückner, M Schmitt, A Fink, G Ladurner… - Physical Review X, 2022 - APS
Cell migration in confining physiological environments relies on the concerted dynamics of
several cellular components, including protrusions, adhesions with the environment, and the …