User profiles for George A. Truskey

George Truskey

Professor of Biomedical Engineering, Duke University
Verified email at duke.edu
Cited by 12881

Endothelial, cardiac muscle and skeletal muscle exhibit different viscous and elastic properties as determined by atomic force microscopy

…, WM Reichert, WE Kraus, GA Truskey - Journal of …, 2001 - Elsevier
This study evaluated the hypothesis that, due to functional and structural differences, the
apparent elastic modulus and viscous behavior of cardiac and skeletal muscle and vascular …

Apparent elastic modulus and hysteresis of skeletal muscle cells throughout differentiation

…, S Zhang, WE Kraus, GA Truskey - American Journal of …, 2002 - journals.physiology.org
The effect of differentiation on the transverse mechanical properties of mammalian myocytes
was determined by using atomic force microscopy. The apparent elastic modulus increased …

Engineering the tissue which encapsulates subcutaneous implants. I. Diffusion properties

AA Sharkawy, B Klitzman, GA Truskey… - Journal of Biomedical …, 1997 - Wiley Online Library
This report uses normal rat subcutis as a reference point to provide a quantitative analysis of
small analyte transport through the tissue which encapsulates implants. Polyvinyl alcohol (…

Bioengineered human myobundles mimic clinical responses of skeletal muscle to drugs

L Madden, M Juhas, WE Kraus, GA Truskey, N Bursac - elife, 2015 - elifesciences.org
10.7554/eLife.04885.001 Existing in vitro models of human skeletal muscle cannot recapitulate
the organization and function of native muscle, limiting their use in physiological and …

[HTML][HTML] Atomic force and total internal reflection fluorescence microscopy for the study of force transmission in endothelial cells

AB Mathur, GA Truskey, WM Reichert - Biophysical journal, 2000 - cell.com
This paper describes the combined use of atomic force microscopy (AFM) and total internal
reflection fluorescence microscopy (TIRFM) to examine the transmission of force from the …

Hemodynamic parameters and early intimal thickening in branching blood vessels

…, PW Longest, JP Archie Jr, GA Truskey - Critical Reviews™ in …, 2001 - dl.begellhouse.com
Intimal thickening due to atherosclerotic lesions or intimal hyperplasia in medium to large
blood vessels is a major contributor to heart disease, the leading cause of death in the Western …

Effect of the conformation and orientation of adsorbed fibronectin on endothelial cell spreading and the strength of adhesion

…, SS Saavedra, GA Truskey - Journal of Biomedical …, 1993 - Wiley Online Library
The effect of surface hydrophobicity upon the conformation of the cell binding domain of
fibronectin (Fn) and the influence of Fn conformation on bovine aortic endothelial cell (BAEC) …

[HTML][HTML] The NIH somatic cell genome editing program

…, MC Skala, AF Tarantal, JC Tilton, GA Truskey… - Nature, 2021 - nature.com
The move from reading to writing the human genome offers new opportunities to improve
human health. The United States National Institutes of Health (NIH) Somatic Cell Genome …

Engineering the tissue which encapsulates subcutaneous implants. II. Plasma–tissue exchange properties

AA Sharkawy, B Klitzman, GA Truskey… - Journal of Biomedical …, 1998 - Wiley Online Library
This study assesses the plasma–tissue exchange characteristics of the capsular tissue that
forms around implants and how they are affected by implant porosity. The number of vessels …