Ebola virus disease in humans is highly lethal, with case fatality rates ranging from 25 to 90%.
There is no licensed treatment or vaccine against the virus, underscoring the need for …

Background. Recently, the use of megadoses of CD34+ hematopoietic progenitors has been
reported to abrogate resistance to engraftment, thus overcoming major histocompatibility …

Influenza virus is characterized by frequent and unpredictable changes of the surface
glycoproteins which enable the virus to escape the immune system. Approved vaccines which …

Background Previous studies suggest that cases of Ebola virus disease (EVD) may go
unreported because they are asymptomatic or unrecognized, but evidence is limited by study …

The emergence of rapidly spreading variants of severe acute respiratory syndrome coronavirus
2 (SARS-CoV-2) poses a major challenge to the ability of vaccines and therapeutic …

Background. Transplantation of human kidney tissue under the kidney capsule of immunodeficient
animals (severe combined immunodeficiency [SCID]/Lewis and SCID/nude chimeric …

Correlates between immunological parameters and protection against Bacillus anthracis
infection in animals vaccinated with protective antigen (PA)-based vaccines could provide …

The emergence of antibiotic-resistant bacteria is a pressing public health concern, highlighting
the need for alternative approaches to control bacterial infections. Promising approaches …

Protective antigen (PA)-based vaccination is an effective countermeasure to anthrax infection.
While neutralizing anti-PA antibody titers elicited by this vaccine serve as good correlates …

In chronic hepatitis B virus (HBV) infection weak antiviral immune responses are associated
with viral persistence. We studied possible immune deficits underlying the lack of serum …