The anti-neutrophil cytoplasmic antibody (ANCA)-associated vasculitides (AAVs) are a group
of disorders involving severe, systemic, small-vessel vasculitis and are characterized by …

Chronic kidney disease (CKD) is defined by persistent urine abnormalities, structural
abnormalities or impaired excretory renal function suggestive of a loss of functional nephrons. The …

Receptor-interacting protein kinase 3 (RIPK3)-mediated necroptosis is thought to be the
pathophysiologically predominant pathway that leads to regulated necrosis of parenchymal …

The global nephrology community recognises the need for a cohesive plan to address the
problem of chronic kidney disease (CKD). In July, 2016, the International Society of …

The kidneys are frequently targeted by pathogenic immune responses against renal autoantigens
or by local manifestations of systemic autoimmunity. Recent studies in rodent models …

Acute kidney injury (AKI) is defined by a sudden loss of excretory kidney function. AKI is part
of a range of conditions summarized as acute kidney diseases and disorders (AKD), in …

Objective To update the 2012 EULAR/ERA–EDTA recommendations for the management of
lupus nephritis (LN). Methods Following the EULAR standardised operating procedures, a …

SARS-CoV-2 infection poses a major threat to the lungs and multiple other organs,
occasionally causing death. Until effective vaccines are developed to curb the pandemic, it is …

The increasing global prevalence of type 2 diabetes mellitus (T2DM) and chronic kidney
disease (CKD) has prompted research efforts to tackle the growing epidemic of diabetic kidney …

Chronic kidney disease (CKD) and end-stage renal disease (ESRD) are associated with
systemic inflammation and acquired immunodeficiency, which promote cardiovascular disease, …