[HTML][HTML] Low volume aseptic filling: Impact of pump systems on shear stress

T Dreckmann, J Boeuf, IS Ludwig, J Lümkemann… - European Journal of …, 2020 - Elsevier
Low volume aseptic filling of parenterals, particularly monoclonal antibodies is becoming
increasingly important with the development of more and more intravitreal drugs and high …

[PDF][PDF] New processes for freeze-drying in dual chamber systems

T Werk, IS Ludwig, J Luemkemann… - PDA J. Pharm. Sci …, 2016 - researchgate.net
2 ice crystals. Compared to the established process, drying times were reduced by half using
the 1 new processes. The drying time was however, longer for syringes compared to vials …

[PDF][PDF] Low-volume aseptic filling using a linear peristaltic pump

T Dreckmann, IS Ludwig, J Luemkemann… - PDA J. Pharm. Sci …, 2021 - researchgate.net
The pharmaceutical industry has been confronted with new and complex challenges,
particularly with regard to the aseptic filling of parenterals, including monoclonal antibodies and …

Assessment of sensor concepts for 100% in-process control of low-volume aseptic fill-finish processes

…, J TrÖndle, A Ernst, J Huwyler, IS Ludwig… - PDA Journal of …, 2020 - journal.pda.org
The pharmaceutical industry is currently being confronted with new and complex challenges
regarding the aseptic filling of parenterals, especially monoclonal antibodies, particularly for …

A method to determine the kinetics of solute mixing in liquid/liquid formulation dual-chamber syringes

T Werk, HC Mahler, IS Ludwig… - PDA journal of …, 2017 - journal.pda.org
Dual-chamber syringes were originally designed to separate a solid substance and its
diluent. However, they can also be used to separate liquid formulations of two individual drug …

[PDF][PDF] Assessment of sensor concepts for a 100% in-process control

T Dreckmann, IS Ludwig, J Luemkemann - researchgate.net
The pharmaceutical industry is currently being confronted with new and complex challenges
regarding the aseptic filling of parenterals, especially monoclonal antibodies, particularly fill …

Low Volume Aseptic Filling of Monoclonal Antibodies

T Dreckmann - 2021 - edoc.unibas.ch
The basic idea of targeted drug therapy was already described in the late 19th century by
Paul Ehrlich referred as "magic bullet". This idea is already reality today and there are many …

[HTML][HTML] 극저온 자체 가압 공정을 위한 인기 있는 액체-증기상 변화 모델의 타당성 평가

레이, 용접, 주조 - International Journal of Heat and Mass Transfer, 2021 - flow3d.co.kr
Liquid-vapor phase change models vitally influence the simulation of self-pressurization
processes in closed containers. Popular liquid-vapor phase change models, such as the Hertz-…

[HTML][HTML] 316-L 스테인리스강의 레이저 분말 베드 융합중 콜드 스패터 형성의 충실도 높은 수치 모델링

M BAYAT, JH HATTEL - flow3d.co.kr
Spatter and denudation are two very well-known phenomena occurring mainly during the
laser powder bed fusion process and are defined as ejection and displacement of powder …