COVID-19 patients at risk of severe disease may be treated with neutralising monoclonal
antibodies (mAbs). To minimise virus escape from neutralisation these are administered as …

Efflux pumps are widely implicated in antibiotic resistance because they can extrude the
majority of clinically relevant antibiotics from within cells to the extracellular environment. …

Klebsiella pneumoniae is an opportunistic pathogen that is often difficult to treat due to its
multidrug resistance (MDR). We have previously shown that K. pneumoniae strains are able to …

There is an urgent need to develop simple and fast antimicrobial susceptibility tests (ASTs)
that allow informed prescribing of antibiotics. Here, we describe a label-free AST that can …

The opportunistic pathogen Acinetobacter baumannii is able to persist in the environment
and is often multidrug resistant (MDR), causing difficulties in the treatment of infections. Here, …

Antimicrobial resistance represents a significant challenge to future healthcare provision. An
acronym ESKAPEE has been derived from the names of the organisms recognised as the …

Antibiotic resistance represents a significant threat to the modern healthcare provision. The
ESKAPEE pathogens (Enterococcus faecium., Staphylococcus aureus, Klebsiella …

The global increase in multi-drug-resistant bacteria is severely impacting our ability to
effectively treat common infections. For Gram-negative bacteria, their intrinsic and acquired …

Staphylococcus aureus infections of the skin and soft tissue pose a major concern to public
health, largely owing to the steadily increasing prevalence of drug resistant isolates. As an …

Worldwide, Klebsiella pneumoniae is an increasingly problematic opportunistic pathogen,
with the emergence of carbapenem-resistant isolates of special importance. The mechanisms …