High product titer is considered a strategic advantage of fed-batch over perfusion
cultivationmode. The titer difference has been experimentally demonstrated and reported in the …

Human interleukin 2 (IL-2; Proleukin) is an approved therapeutic for advanced-stage metastatic
cancer; however, its use is restricted because of severe systemic toxicity. Its function as a …

On‐line monitoring and control of cell culture fermentation is important for optimal and
consistent production of biologicals. In this work, glucose and lactate concentrations are …

Virtual reality (VR) is an emerging technology that can provide a nonpharmacological
approach to symptom management for those with serious illnesses. The VR platform offers a …

We live in an unusual historical period in that the business of economic analysis has become
associated not just with one discipline, but with one part of one discipline. Economics, and …

This paper is a preliminary attempt to work out what a nonfunctionalist social theory which
still retains the crucial element of determination would look like. The paper is therefore …

Production of coagulation factor VIII (FVIII) by recombinant cell lines is limited by its failure to
reach or maintain the native conformation in the endoplasmic reticulum. This results in …

On‐line optical cell density probes were implemented to continuously monitor the cell densities
in mammalian cell bioreactor and to achieve advanced bioreactor controls. We tested …

In human geography, as in other social sciences, much recent work has focused on
contemporary consumption practices. The aim of this paper is to bring historical perspectives on …

The engineering of production cell lines to express anti‐apoptotic genes has been pursued
in recent years due to potential process benefits, including enhanced cell survival, increased …