Lipids have been used extensively for drug delivery in various forms such as liposomes,
and solid-matrices. The focus of this review is evaluation of liquid crystalline cubic phases, …

Proteolysis targeting chimeras (PROTACs) are heterobifunctional small molecules that
simultaneously bind to a target protein and an E3 ligase, thereby leading to ubiquitination and …

This literature review presents hydrolysis of active pharmaceutical ingredients as well as the
effects on dosage form stability due to hydrolysis of excipients. Mechanisms and …

The overall objective was to design and evaluate biodegradable implants for local drug
delivery in clinical conditions and/or diseases described below, which are currently treated with …

The emulsion-based topical semisolid dosage forms present a high degree of complexity
due to their microstructures which is apparent from their compositions comprising at least two …

Purpose The aim of this study was to develop quantitative structure pharmacokinetic relationships
(QSPKR) to correlate drug physicochemical properties (molecular weight, lipophilicity, …

Etoposide, an anticancer drug, has low and erratic oral bioavailability which is due to low
aqueous solubility, slow dissolution rate and instability in acidic pH. The study objective was to …

Preformulation studies of etoposide, including pH–solubility profile, partition coefficient, pH–stability
profile, and in vitro dissolution kinetics, were conducted to identify the responsible …

The main objective of the study was to evaluate if the liquid crystalline cubic phase gel of
glyceryl monooleate (GMO) protects insulin from agitation induced aggregation. The …

Shrimp are among the most highly valued seafood in the US, and a large proportion are
cultured. At least seven species of Vibrio bacteria and other pathogens often infect shrimp …