Secreted semaphorins are a large group of extracellular proteins involved in a variety of
processes during development, including neuronal migration and axon guidance. We screened …

Calcineurin phosphatase plays a crucial role in T cell activation. Dephosphorylation of the
nuclear factors of activated T cells (NFATs) by calcineurin is essential for activating cytokine …

A positional scanning library of 625 N-alkylglycine pentamers has been synthesized on solid-phase,
employing a set of 10 commercially available primary amines as a source of …

Calcineurin is a Ca 2+ /calmodulin-dependent serine/threonine protein phosphatase involved
in many biological processes and developmental programs, including immune response. …

A study on the preparation of N-alkylglycines (peptoids) that contain tertiary amino residues
on the N-alkyl side chains is reported. The appropriate combination of the submonomer …

Manufacturers of human plasma-derived products ensure, through their qualification
departments, the quality and safety of human plasma—the biological starting material of the …

The exploration of the universe has recently entered a new era thanks to the multi-messenger
paradigm, characterized by a continuous increase in the quantity and quality of …

New 3-oxopiperazinium derivatives agonists of Nerve Growth Factor receptors and their use
as medicaments. Neurotrophin binding to its specific receptor Trk A leads to the activation of …

New 3-oxopiperazinium derivatives agonists ofNerve Growth Factor receptors and their use
as medicaments. Neurotrophin binding to its specific receptor Trk A leads to the activation of …

[cat] La recerca en el camp del desenvolupament de fàrmacs peptídics i peptidomimètics ha
experimentat una evolució important durant els darrers anys. Els fàrmacs peptídics sovint …