There is strong interest in the design of bispecific monoclonal antibodies (bsAbs) that can
simultaneously bind 2 distinct targets or epitopes to achieve novel mechanisms of action and …

Therapeutic proteins including monoclonal antibodies (mAbs) are usually produced in
engineered host cell lines that also produce thousands of endogenous proteins at varying levels. …

Purpose Polysorbates (PS) are excipients used in the biotech industry to stabilize monoclonal
antibody (mAb) protein products. However, PS in drug product formulations can be …

Considerable resources are spent within the biopharmaceutical industry to perform viral
clearance studies, which are conducted for widely used unit operations that are known to have …

T HE current revival of interest in regional economic research has been quietly undergoing
a subtle shift in areal orientation. Increasingly, emphasis has been diverted from the …

Polysorbates (PS) are surfactants commonly added in a therapeutic protein drug product as
excipients to protect proteins from denaturation and aggregation during storage, …

Highlights • Speed and need of the COVID-19 treatment started with Regeneron platform
technologies. • Regeneron and Genentech used considerable monoclonal antibody …

Characterization of ionic strength for Xâ•’MuLV inactivation by low pH treatment for
monoclonal antibody purification Page 1 This article has been accepted for publication and …

… See Kendrick and Jaycox [13], Gross Metropolitan Product in Metropolitan Chicago [10],
and Mattila [15]. … * All of the data for the variables appearing in this model, with the …

The present work is an investigation of intrametropolitan agglomeration of industry in Detroit.
In dealing with intra-as opposed to intermetropolitan location, the analysis focuses attention …