Surfactant-laden soft contact lenses for extended delivery of ophthalmic drugs
Eye drops are inefficient means of delivering ophthalmic drugs because of limited bioavailability
and these can cause significant side effects due to systemic uptake of the drug. The …
and these can cause significant side effects due to systemic uptake of the drug. The …
[HTML][HTML] Interfacial stress in the development of biologics: fundamental understanding, current practice, and future perspective
Biologic products encounter various types of interfacial stress during development, manufacturing,
and clinical administration. When proteins come in contact with vapor–liquid, solid–…
and clinical administration. When proteins come in contact with vapor–liquid, solid–…
Effect of single-point mutations on the stability and immunogenicity of a recombinant ricin A chain subunit vaccine antigen
JC Thomas, JM O'Hara, L Hu, FP Gao… - Human vaccines & …, 2013 - Taylor & Francis
There is great interest in the design and development of highly thermostable and immunogenic
protein subunit vaccines for biodefense. In this study, we used two orthogonal and …
protein subunit vaccines for biodefense. In this study, we used two orthogonal and …
Drug formulation impact on prefilled syringe functionality and autoinjector performance
…, CADÈ Richard, X Dong, JC Thomas… - PDA Journal of …, 2020 - journal.pda.org
Given the surging interest in developing prefilled syringe and autoinjector combination
products, investment in an early compatibility assessment is critical to prevent unwarranted drug/…
products, investment in an early compatibility assessment is critical to prevent unwarranted drug/…
Novel ricin subunit antigens with enhanced capacity to elicit toxin-neutralizing antibody responses in mice
N Wahome, E Sully, C Singer, JC Thomas, L Hu… - Journal of …, 2016 - Elsevier
… The single point mutation precursors were computed by Justin C. Thomas, Jianwen Fang, …
Thomas acknowledges financial support from NIH T32 GM008359 and a pre-doctoral …
Thomas acknowledges financial support from NIH T32 GM008359 and a pre-doctoral …
The physical analysis of vaccines
Y Cheng, JC Thomas, SB Joshi, DB Volkin… - Subunit Vaccine …, 2015 - Springer
The analysis of the structural integrity of biotechnology products and macromolecular systems
has become increasingly sophisticated. With regard to vaccines, the major problem has …
has become increasingly sophisticated. With regard to vaccines, the major problem has …
[HTML][HTML] The consequences of nuclear transfer for mammalian foetal development and offspring survival. A mitochondrial DNA perspective
JC St John, REI Lloyd, EJ Bowles, EC Thomas… - …, 2004 - rep.bioscientifica.com
The introduction of nuclear transfer (NT) and other technologies that involve embryo
reconstruction require us to reinvestigate patterns of mitochondrial DNA (mtDNA) transmission, …
reconstruction require us to reinvestigate patterns of mitochondrial DNA (mtDNA) transmission, …
[HTML][HTML] Synthesis and characterization of superparamagnetic iron-oxide nanoparticles (SPIONs) and utilization of SPIONs in X-ray imaging
C Justin, SA Philip, AV Samrot - Applied Nanoscience, 2017 - Springer
The versatility of superparamagnetic iron-oxide nanoparticles (SPIONs) have been
extensively investigated, especially for their applications in therapeutics and diagnostics. …
extensively investigated, especially for their applications in therapeutics and diagnostics. …
Limits to anatomical accuracy of diffusion tractography using modern approaches
Diffusion MRI fiber tractography is widely used to probe the structural connectivity of the brain,
with a range of applications in both clinical and basic neuroscience. Despite widespread …
with a range of applications in both clinical and basic neuroscience. Despite widespread …
Au/TiO2–gC3N4 Nanocomposites for Enhanced Photocatalytic H2 Production from Water under Visible Light Irradiation with Very Low Quantities of Sacrificial …
…, C Colbeau‐Justin… - Advanced Energy …, 2018 - Wiley Online Library
Here for the first time the design and optimization are presented of a three‐component Au/TiO
2 –gC 3 N 4 nanocomposite photocatalyst able to efficiently produce H 2 from water using …
2 –gC 3 N 4 nanocomposite photocatalyst able to efficiently produce H 2 from water using …