Indinavir is a protease inhibitor used in the treatment of HIV infection. However, it has limited
efficacy in eradicating the virus in the brain due to efflux by P-glycoprotein (P-gp) expressed …

The current study was aimed to investigate the potential of solid self-nanoemulsifying drug
delivery system (S-SNEDDS) composed of Capmul MCM C8 (oil), Tween 80 (surfactant) and …

The present systematic study focused to investigate the combined advantage of
proliposomes and surface charge for improved oral delivery of zaleplon. The zaleplon loaded …

The primary goal of the present study was to investigate the combined prospective of
proliposomes and surface charge for the improved oral delivery of raloxifene hydrochloride (RXH). …

Isradipine (ISR) is a potent calcium channel blocker with low oral bioavailability due to low
aqueous solubility, extensive first-pass metabolism and P-glycoprotein (P-gp)-mediated efflux …

Indinavir, an antiretroviral protease inhibitor used in treatment of HIV infection has limited
penetration into brain due to efflux of P-glycoprotein. The aim of this work was to develop …

The aim of this study was to develop stable parenteral pegylated indinavir submicron lipid
emulsions (SLEs) for improving brain specific delivery. The O/W SLEs were prepared by …

Diclofenac lipid nanoemulsions (DLNEs) were prepared with different compositions. Based
on size, PDI, zeta potential, and in vitro drug release, the optimized DLNEs (DLNE-4 and …

The main objective of this work was to prepare a self-micro emulsifying drug delivery system
(SMEDDS) for enhancement of oral bioavailability of domperidone, a poorly water soluble …

Self-nanoemulsifying drug delivery systems (SNEDDSs) offer potential as suitable carriers
for improved oral delivery of poorly soluble and low bioavailable drugs. To derive self-…