Objectives Exosomes are 50–90 nm extracellular membrane particles that may mediate
trans-cellular communication between cells and tissues. We have reported that human urinary …

The C2 domain is a ubiquitous Ca 2+ -binding motif that triggers the membrane docking of
many key signaling proteins during intracellular Ca 2+ signals. Site-directed spin labeling …

The attractive interaction between basic protein domains and membranes containing acidic
lipids is critical to the membrane attachment of many proteins involved in cell signaling. In …

The vesicular stomatitis virus (VSV) RNA-dependent RNA polymerase consists of two viral
proteins; the large (L) protein is the main catalytic subunit, and the phosphoprotein (P) is an …

USP <1207.1> Section 3.5 states that “A deterministic leak test method having the ability to
detect leaks at the product's maximum allowable leakage limit is preferred when establishing …

Signal transduction pathways that are modulated by thiol oxidation events are beginning to
be uncovered, but these discoveries are limited by the availability of relatively few analytical …

The dismantling and elimination of excess neurons and their connections (pruning) is
essential for brain development and may be aberrantly reactivated in some neurodegenerative …

The residual water-proton magnetic relaxation dispersion profile obtained from suspensions
of phospholipid vesicles in deuterium oxide was found to be a logarithmic function of the …

Peptide sequence identification using tandem mass spectroscopy remains a major
challenge for complex proteomic studies. Peptide matching algorithms require the accurate …

The magnetic field dependence of the nuclear spin–lattice relaxation rate constant defines
the magnetic relaxation dispersion (MRD) and provides a direct characterization of the …