Depth filtration: cell clarification of bioreactor offloads

M Prashad, K Tarrach - Filtration & separation, 2006 - Elsevier
… Author links open overlay panel Mahesh Prashad (Head of product management) a ,
Klaus Tarrach (Senior product manager) b … Sartorius' Mahesh Prashad and Klaus Tarrach …

A consensus rating method for small virus-retentive filters. I. Method development

…, J Campbell, P Genest, S Dolan, K Tarrach… - PDA Journal of …, 2008 - journal.pda.org
Virus filters are membrane-based devices that remove large viruses (eg, retroviruses) and/or
small viruses (eg, parvoviruses) from products by a size exclusion mechanism. In 2002, the …

A consensus rating method for small virus-retentive filters. II. Method evaluation

…, J Parrella, S Dolan, S Martin, K Tarrach… - PDA Journal of …, 2008 - journal.pda.org
Virus filters are membrane-based devices that remove large viruses (eg, retroviruses) and/or
small viruses (eg, parvoviruses) from products by a size exclusion mechanism. In 2002, the …

The effect of flux decay on a 20-nm nanofilter for virus retention: in a single stage of the downstream purification process, 20-nm namofilters can clear both large and …

K Tarrach, A Meyer, JE Dathe, H Sun - BioPharm International, 2007 - go.gale.com
KLAUS TARRACH is the senior product manager of purification technologies, +49 551.308.3959,
klaus.tarrach@sartorius.com, ANIKA MEYER is an application specialist in purification …

[HTML][HTML] Viral clearance strategy using a three-tier orthogonal technology platform

S Ray, K Tarrach - BioPharm International, 2008 - biopharminternational.com
Removing viral contaminants from animal cell-culture derived biologicals is a major challenge
of downstream purification because it involves laborious and time-consuming techniques …

[PDF][PDF] Robustness of parvovirus‐retentive membranes and implications for virus clearance validation requirements

…, E Charbaut, JE Dathe, K Tarrach… - BioProcess …, 2009 - eu-assets.contentstack.com
A regulatory challenge: In the context of quality by design and risk-based quality management,
regulatory agencies will be placing a greater emphasis on process knowledge and on the …

[HTML][HTML] Integration of Large-Scale Chromatography with Nanofiltration for an Ovine Polyclonal Product

K Tarrach, C Jones, A Denton - Pharmaceutical Technology, 2009 - pharmtech.com
Klaus TarrachKlaus Tarrach is a senior product manager of purification technologies
at Sartorius … Tarrach, "Virus Filter Positioning in the Purification Process of Cell Culture …

[HTML][HTML] Filtration: Vendor Notes: The Effect of Flux Decay on a 20-nm Nanofilter for Virus Retention

…, H Sun, J Dathe, K Tarrach - BioPharm …, 2007 - biopharminternational.com
Viral clearance steps are essential for maintaining the safety and integrity of biopharmaceutical
products. ICH Q5A mandates that the manufacturing process remove or inactivate …

Managing initial recovery processes with multilayer depth filtration

K Köhler, C Grimm, K Tarrach - Pharmaceutical Technology Europe, 2008 - pharmtech.com
Klaus TarrachKlaus Tarrach is a senior product manager of purification technologies. …
Tarrach, "Development and production of antibodies, vaccines and gene vectors", WilBioÂs …

[CITATION][C] Validation and quality procedures for virus and prion removal in biopharmaceuticals

A Immelmann, K Kellings, O Stamm, K Tarrach - BioProcess Int, 2005