Compiling packet programs to reconfigurable switches

L Jose, L Yan, G Varghese, N McKeown - 12th USENIX Symposium on …, 2015 - usenix.org
Programmable switching chips are becoming more commonplace, along with new packet
processing languages to configure the forwarding behavior. Our paper explores the design of …

Learning networking by reproducing research results

L Yan, N McKeown - ACM SIGCOMM Computer Communication Review, 2017 - dl.acm.org
In the past five years, the graduate networking course at Stanford has assigned over 200
students the task of reproducing results from over 40 networking papers. We began the project …

High speed networks need proactive congestion control

L Jose, L Yan, M Alizadeh, G Varghese… - Proceedings of the 14th …, 2015 - dl.acm.org
As datacenter speeds scale to 100 Gb/s and beyond, traditional congestion control algorithms
like TCP and RCP converge slowly to steady sending rates, which leads to poorer and …

Introducing an implicit membrane in generalized Born/solvent accessibility continuum solvent models

VZ Spassov, L Yan, S Szalma - The Journal of Physical Chemistry …, 2002 - ACS Publications
A new empirical approach to model the solvent effects in protein−membrane complexes is
proposed. The generalized Born (GB) approximation is extended by including an implicit …

Fully automated molecular mechanics based induced fit protein− ligand docking method

J Koska, VZ Spassov, AJ Maynard, L Yan… - Journal of chemical …, 2008 - ACS Publications
We describe a method for docking a ligand into a protein receptor while allowing flexibility
of the protein binding site. The method employs a multistep procedure that begins with the …

The evolving field of human papillomavirus receptor research: a review of binding and entry

…, AW Woodham, LM Raff, JG Skeate, L Yan… - Journal of …, 2013 - Am Soc Microbiol
Human papillomaviruses (HPVs) infect epithelia and can lead to the development of lesions,
some of which have malignant potential. HPV type 16 (HPV16) is the most oncogenic …

A fast and accurate computational approach to protein ionization

VZ Spassov, L Yan - Protein Science, 2008 - Wiley Online Library
We report a very fast and accurate physics‐based method to calculate pH‐dependent
electrostatic effects in protein molecules and to predict the pK values of individual sites of titration. …

LOOPER: a molecular mechanics-based algorithm for protein loop prediction

VZ Spassov, PK Flook, L Yan - Protein Engineering, Design & …, 2008 - academic.oup.com
We describe a new ab initio method and corresponding program, LOOPER, for the
prediction of protein loop conformations. The method is based on a multi-step algorithm (developed …

The dominant role of side‐chain backbone interactions in structural realization of amino acid code. ChiRotor: a side‐chain prediction algorithm based on side‐chain …

VZ Spassov, L Yan, PK Flook - Protein Science, 2007 - Wiley Online Library
The basic differences between the 20 natural amino acid residues are due to differences in
their side‐chain structures. This characteristic design of protein building blocks implies that …

[HTML][HTML] Fully automated antibody structure prediction using BIOVIA tools: Validation study

H Kemmish, M Fasnacht, L Yan - PloS one, 2017 - journals.plos.org
We describe the methodology and results from our validation study of the fully automated
antibody structure prediction tool available in the BIOVIA (formerly Accelrys) protein modeling …