The “Guidelines on the Management of Valvular Heart Disease” were initially published as
the “Guidelines on Non-pharmacological Treatment of Valvular Heart Disease” in 2002, …

Background : Current guidelines generally recommend watchful waiting until symptoms emerge
for aortic valve replacement (AVR) in asymptomatic patients with severe aortic stenosis (…

This paper provides an updated review of world tuna fisheries. Previous studies (Miyake et
al., 2004) discussed the historical development of tuna fisheries, described current world tuna …

The total world catch of the major commercial tuna species (albacore, bigeye, bluefin, skipjack
and yellowfin) has increased during the last 50 years (from 0.4 to 3.9 million tonnes), but …

Aim: Severe gastrointestinal bleeding sometimes occurs in patients with aortic stenosis (AS),
known as Heyde's syndrome. This syndrome is thought to be caused by acquired von …

Background: Severe tricuspid regurgitation (TR) sometimes develops late after left-sided
valve surgery without left heart failure, pulmonary hypertension or rheumatic tricuspid valve. …

Objectives We sought to evaluate the prognostic impact of the B-type natriuretic peptide (BNP)
levels in patients with asymptomatic severe aortic stenosis (AS), who were not referred for …

Whether patients with severe aortic stenosis (AS) die because of AS-related causes is an
important issue for the management of these patients. We used data from CURRENT AS …

Background: Clinical profiles of acute heart failure (AHF) complicating severe aortic stenosis
(AS) remain unclear. Methods and Results: From a Japanese multicenter registry enrolling …

Background: There is a paucity of data on the sex differences in the prevalence, clinical
presentation, and prognosis of aortic stenosis (AS). Methods and Results: A total of 3,815 …