User profiles for Michael Walsh

Michael Walsh

- Verified email at phri.ca - Cited by 23057

Michael Walsh

- Verified email at snp.com.au - Cited by 14302

Michael F Walsh

- Verified email at mskcc.org - Cited by 11458

Immune checkpoint inhibition for hypermutant glioblastoma multiforme resulting from germline biallelic mismatch repair deficiency

…, G Rechavi, V Magimairajan, MF Walsh… - Journal of clinical …, 2016 - ascopubs.org
Purpose Recurrent glioblastoma multiforme (GBM) is incurable with current therapies. Biallelic
mismatch repair deficiency (bMMRD) is a highly penetrant childhood cancer syndrome …

[HTML][HTML] Rituximab versus cyclophosphamide in ANCA-associated renal vasculitis

…, P van Paassen, D Walsh, M Walsh… - … England Journal of …, 2010 - Mass Medical Soc
Background Cyclophosphamide induction regimens for antineutrophil cytoplasmic antibody
(ANCA)–associated vasculitis are effective in 70 to 90% of patients, but they are associated …

A functional genomics strategy that uses metabolome data to reveal the phenotype of silent mutations

…, D Broadhurst, N Zhang, A Hayes, MC Walsh… - Nature …, 2001 - nature.com
A large proportion of the 6,000 genes present in the genome of Saccharomyces cerevisiae,
and of those sequenced in other organisms, encode proteins of unknown function. Many of …

[HTML][HTML] Inherited DNA-repair gene mutations in men with metastatic prostate cancer

CC Pritchard, J Mateo, MF Walsh… - … England Journal of …, 2016 - Mass Medical Soc
Background Inherited mutations in DNA-repair genes such as BRCA2 are associated with
increased risks of lethal prostate cancer. Although the prevalence of germline mutations in …

[HTML][HTML] Germline mutations in predisposition genes in pediatric cancer

J Zhang, MF Walsh, G Wu, MN Edmonson… - … England Journal of …, 2015 - Mass Medical Soc
Background The prevalence and spectrum of predisposing mutations among children and
adolescents with cancer are largely unknown. Knowledge of such mutations may improve the …

Using Fourier transform IR spectroscopy to analyze biological materials

…, GD Sockalingum, J Sulé-Suso, RJ Strong, MJ Walsh… - Nature protocols, 2014 - nature.com
IR spectroscopy is an excellent method for biological analyses. It enables the nonperturbative,
label-free extraction of biochemical information and images toward diagnosis and the …

Sodium-glucose cotransporter protein-2 (SGLT-2) inhibitors and glucagon-like peptide-1 (GLP-1) receptor agonists for type 2 diabetes: systematic review and network …

…, R Rodriguez-Gutierrez, M Walsh… - Bmj, 2021 - bmj.com
Objective To evaluate sodium-glucose cotransporter-2 (SGLT-2) inhibitors and glucagon-like
peptide-1 (GLP-1) receptor agonists in patients with type 2 diabetes at varying …

Relationship between intraoperative mean arterial pressure and clinical outcomes after noncardiac surgery: toward an empirical definition of hypotension

M Walsh, PJ Devereaux, AX Garg, A Kurz, A Turan… - …, 2013 - pubs.asahq.org
Background: Intraoperative hypotension may contribute to postoperative acute kidney injury
(AKI) and myocardial injury, but what blood pressures are unsafe is unclear. The authors …

The genomic landscape of hypodiploid acute lymphoblastic leukemia

L Holmfeldt, L Wei, E Diaz-Flores, M Walsh, J Zhang… - Nature …, 2013 - nature.com
The genetic basis of hypodiploid acute lymphoblastic leukemia (ALL), a subtype of ALL
characterized by aneuploidy and poor outcome, is unknown. Genomic profiling of 124 …

Using Raman spectroscopy to characterize biological materials

…, B Gardner, PL Martin-Hirsch, MJ Walsh… - Nature protocols, 2016 - nature.com
Raman spectroscopy can be used to measure the chemical composition of a sample, which
can in turn be used to extract biological information. Many materials have characteristic …