A new cascade impactor has been designed specifically for pharmaceutical inhaler testing.
This impactor, called the Next Generation Pharmaceutical Impactor (NGI), has seven stages …

Purpose. To examine the effect of particle size and morphology on aerosol dispersion using
jet-milled and spray-dried mannitol particles in narrow size distributions within the respirable …

Purpose. To examine the effect of formulation type on the aerosolization of respirable
particles in narrow size distributions. Methods. Aerosol dispersion of two formulation types (drug …

A series of standardized entrainment tubes (SETs) were designed to provide a method for
evaluation of aerosol dispersion of pharmaceutical powders. The range of specific resistances …

There is increasing focus on the development of dry powder inhalers (DPIs) for the delivery
of therapeutic entities to the lungs. In vitro testing of metered-dose inhalers (MDIs) has …

A novel method is described that compares the in vitro drug delivery characteristics of different
dry powder inhalers (DPIs) based on the power supplied by the air flow. Power is defined …

An automated adiabatic calorimeter with an internal volume of 5 cm 3 , operable over the
temperature range from 30 to 380 K is described. One of the main advantages of this …

Over the lifecycle of an orally inhaled product (OIP), multi-stage cascade impactor (CI)
measurements are used for different purposes and to address different questions. Full-resolution …

The ultimate aim of the various particle generation techniques used in pharmaceutical inhalation
products is to create respirable particles for either the treatment of respiratory diseases …

The heat capacities of four di‐n‐alkylammonium chlorides (di‐n‐pentylammonium chloride,
di‐n‐hexylammonium chloride, di‐n‐octylammonium chloride, and di‐n‐decylammonium …