Purification and Properties of the Heme- and Iron−Sulfur-Containing Heterodisulfide Reductase from Methanosarcina thermophila
M Simianu, E Murakami, JM Brewer, SW Ragsdale - Biochemistry, 1998 - ACS Publications
The heterodisulfide reductase (HDR) from Methanosarcina thermophila was purified to
homogeneity from acetate-grown cells. In the absence of detergents, HDR consisted of an eight-…
homogeneity from acetate-grown cells. In the absence of detergents, HDR consisted of an eight-…
Hydrogen-bonding interactions in the active sites of cytochrome P450cam and its site-directed mutants
T Deng, IDG Macdonald, MC Simianu… - Journal of the …, 2001 - ACS Publications
Resonance Raman spectroscopy is applied to the cyanide adducts of cytochrome P450cam
and its T252A and D251N site-directed mutants, both in their substrate-free and camphor-…
and its T252A and D251N site-directed mutants, both in their substrate-free and camphor-…
Resonance Raman Spectroscopic Detection of Both Linear and Bent Fe-CN Fragments for the Cyanide Adducts of Cytochrome P-450 Camphor and Its Substrate …
MC Simianu, JR Kincaid - Journal of the American Chemical …, 1995 - ACS Publications
The resonance Raman spectra of the cyanide adducts of cytochrome P-450 camphor in the
substrate-free, camphor-bound, and adamantanone-bound forms are reported. Careful …
substrate-free, camphor-bound, and adamantanone-bound forms are reported. Careful …
PDA points to consider: technical product lifecycle management. Pharmaceutical quality system effectiveness for managing post-approval changes
…, M Jornitz, M Munk, M Seymour, M Simianu… - PDA Journal of …, 2017 - journal.pda.org
Background During the commercial manufacturing phase of the product lifecycle, specific
elements of the PQS are used to identify and manage PACs. Per ICH Q10, these include …
elements of the PQS are used to identify and manage PACs. Per ICH Q10, these include …
PDA Points To Consider: Technical Product Lifecycle Management: Communication and Knowledge Exchange between Marketing Authorization Holders and Health …
…, M Jornitz, M Munk, M Seymour, M Simianu… - PDA Journal of …, 2017 - journal.pda.org
… Authors: Members of the PDA Task Force Post Approval Changes for Innovation in
Availability of Medicines (PAC iAM), Emma Ramnarine, Ursula Busse, Marcello Colao, Julia …
Availability of Medicines (PAC iAM), Emma Ramnarine, Ursula Busse, Marcello Colao, Julia …
PDA PAC iAM 2017 Survey on Post Approval Change: Is the Regulatory Environment Hindering Much-Needed Innovation in the Pharma Industry?
…, K O'Donnel, M Seymour, M Simianu… - PDA Journal of …, 2017 - journal.pda.org
… Authors: Members of the PDA Task Force Post Approval Changes for Innovation in
Availability of Medicines (PAC iAM), Emma Ramnarine, Ursula Busse, Marcello Colao, Julia …
Availability of Medicines (PAC iAM), Emma Ramnarine, Ursula Busse, Marcello Colao, Julia …
[BOOK][B] Resonance Raman structural characterization of cyanide ligated cytochrome P450cam
MC Simianu - 1995 - search.proquest.com
INFORMATION TO USERS Page 1 INFORMATION TO USERS This manuscript has been
reproduced from the microfilm master. UMI films the text directly from the original or copy …
reproduced from the microfilm master. UMI films the text directly from the original or copy …
[PDF][PDF] A BREAKTHROUGH FOR INDUSTRY AND PATIENTS
E Whitehead - 2017 - pharmatechassociates.com
… to be defined specifically for each product,” said Mihaela Simianu, PhD, Director of Regulatory …
Simianu. “For example, one may need to ensure that cells arrive at the manufacturing site …
Simianu. “For example, one may need to ensure that cells arrive at the manufacturing site …
[BOOK][B] Zeolite-based organized molecular assemblies and their application to photochemical storage of light energy
M Sykora - 1997 - search.proquest.com
INFORMATION TO USERS Page 1 INFORMATION TO USERS This manuscript has been
reproduced from the microfilm master. UMI films the text directly from the original or copy …
reproduced from the microfilm master. UMI films the text directly from the original or copy …
[PDF][PDF] PDA Paper
E Ramnarine - PDA Journal of Pharmaceutical Science and …, 2017 - scholar.archive.org
Changes occur throughout a product’s commercial life—changes in raw materials, manufacturing
equipment, processes, sites, analytical methods, and suppliers. A product Marketing …
equipment, processes, sites, analytical methods, and suppliers. A product Marketing …