When mannitol solutions were frozen in glass vials at typical rates (0.3–1C/min) and
warmed while monitoring the electrical resistance of the frozen solution, a sharp increase in …

The thermal characteristics as a function of cooling rate of mannitol solutions were studied by
Differential Scanning Calorimetry (DSC). The exotherm appearing during warming at –25 ± …

An approach is developed by which the solubility of an organic compound in mixed solvents
may be estimated. In this approach, an expression for the excess Gibbs free energy of …

The mechanical properties of frozen mannitol, L-iditol, dulcitol, and sorbitol solutions were
measured as a function of temperature during warming (after freezing) using a thermal …

□ The results of this study show that pentamidine isethionate (PI) can exist in at least four
crystalline forms—three anhydrates designated as forms A, B, and C, and a trihydrate. Form C …

Macrolide antibiotics are well-known to cause pain on intravenous injection. The studies
reported here indicate the feasibility of using bile salts, especially bile salt-phospholipid mixed …

The reduced 3-suffix solubility equation (R3SSE) is applied to the characterization of solubility
in the ethanol–water system. The data needed are the solubility of the compound in each …

Pentamidine isethionate is a lyophilized antiprotozoal drug. Its solutions, when lyophilized,
have been found to exhibit a range of properties that depend on its concentration and the …

The effects of size and hydrophobicity of small (molecular weights below 2,000) polypeptides
on their predominantly hydrophobic interactions with a neutral phospholipid monolayer …

The stability of levofloxacin in 10 commonly used infusion fluids was studied. Levofloxacin
25-mg/mL injection was diluted to 0.5 and 5 mg/mL in each of the following iv infusion fluids: …