Dendrimer as nanocarrier for drug delivery
P Kesharwani, K Jain, NK Jain - Progress in Polymer Science, 2014 - Elsevier
Dendrimers are novel three dimensional, hyperbranched globular nanopolymeric architectures.
Attractive features like nanoscopic size, narrow polydispersity index, excellent control …
Attractive features like nanoscopic size, narrow polydispersity index, excellent control …
A PEGylated dendritic nanoparticulate carrier of fluorouracil
The present study was aimed at developing and exploring the use of uncoated and PEGylated
newer PAMAM dendrimers for delivery of anti-cancer drug 5-fluorouracil. For this study, …
newer PAMAM dendrimers for delivery of anti-cancer drug 5-fluorouracil. For this study, …
Dendrimers: novel polymeric nanoarchitectures for solubility enhancement
U Gupta, HB Agashe, A Asthana, NK Jain - Biomacromolecules, 2006 - ACS Publications
Poor solubility and hydrophobicity of drugs/bioactives limit their possible applications in
drug delivery and formulation development. Apart from conventional methods of solubility …
drug delivery and formulation development. Apart from conventional methods of solubility …
Nanoemulsion: Concepts, development and applications in drug delivery
Nanoemulsions are biphasic dispersion of two immiscible liquids: either water in oil (W/O)
or oil in water (O/W) droplets stabilized by an amphiphilic surfactant. These come across as …
or oil in water (O/W) droplets stabilized by an amphiphilic surfactant. These come across as …
Effect of trehalose on protein structure
Trehalose is a ubiquitous molecule that occurs in lower and higher life forms but not in
mammals. Till about 40 years ago, trehalose was visualized as a storage molecule, aiding the …
mammals. Till about 40 years ago, trehalose was visualized as a storage molecule, aiding the …
Calcium silicate based microspheres of repaglinide for gastroretentive floating drug delivery: Preparation and in vitro characterization
SK Jain, AM Awasthi, NK Jain, GP Agrawal - Journal of controlled release, 2005 - Elsevier
Gastroretentive dosage forms have potential for use as controlled-release drug delivery
systems. Multiple unit systems avoid the ‘all-or-none’ gastric emptying nature of single-unit …
systems. Multiple unit systems avoid the ‘all-or-none’ gastric emptying nature of single-unit …
Melatonin loaded ethanolic liposomes: physicochemical characterization and enhanced transdermal delivery
The current investigation aims to evaluate the transdermal potential of novel ethanolic
liposomes (ethosomes) bearing Melatonin (MT), an anti-jet lag agent associated with poor skin …
liposomes (ethosomes) bearing Melatonin (MT), an anti-jet lag agent associated with poor skin …
Formulation and evaluation of ethosomes for transdermal delivery of lamivudine
The purpose of the present research was to investigate the mechanism for improved intercellular
and intracellular drug delivery from ethosomes using visualization techniques and cell …
and intracellular drug delivery from ethosomes using visualization techniques and cell …
Dendrimer toxicity: Let's meet the challenge
Dendrimers are well-defined, versatile polymeric architecture with properties resembling
biomolecules. Dendritic polymers emerged as outstanding carrier in modern medicine system …
biomolecules. Dendritic polymers emerged as outstanding carrier in modern medicine system …
Transfersomes—a novel vesicular carrier for enhanced transdermal delivery: development, characterization, and performance evaluation
…, P Jain, RB Umamaheshwari, NK Jain - Drug development and …, 2003 - Taylor & Francis
This work describes the use of a novel vesicular drug carrier system called transfersomes,
which is composed of phospholipid, surfactant, and water for enhanced transdermal delivery. …
which is composed of phospholipid, surfactant, and water for enhanced transdermal delivery. …