In this study, we used deoxyribozyme (DNAzyme) functionalized gold nanoparticles (AuNPs)
to catalytically silence tumor necrosis factor-α (TNF-α) in vivo as a potential therapeutic for …

Acute myocardial infarction (MI) caused by ischemia and reperfusion (IR) is the most
common cause of cardiac dysfunction due to local cell death and a temporally regulated …

Introduction Administration of bone marrow-derived mesenchymal stem cells (MSCs) after
myocardial infarction (MI) results in modest functional improvements. However; the effect of …

Background This study was inspired by coalescing evidence that magnetic therapy may be
a viable treatment option for certain diseases. This premise is based on the ability of …

Myocardial infarction is the leading cause of death worldwide and phase I clinical trials
utilizing cardiac progenitor cells (CPCs) have shown promising outcomes. Notch1 signaling …

There are a limited number of therapies available to prevent heart failure following myocardial
infarction. One novel therapy that is currently being pursued is the implantation of cardiac …

Background Compelling evidence exists that magnetic fields modulate living systems. To
date, however, rigorous studies have focused on identifying the molecular-level biosensor (eg, …

Since the successful generation of induced pluripotent stem cells (iPSC) from adult somatic
cells using integrating-viral methods, various methods have been tried for iPSC generation …

There is a great need for the development of therapeutic strategies that can target biomolecules
to damaged myocardium. Necrosis of myocardium during a myocardial infarction (MI) is …

Metabolic glycoengineering, a technique pioneered almost two decades ago wherein
monosaccharide analogs are utilized to install non-natural sugars into the glycocalyx of …