User profiles for Paul C. Ho

Paul C. HO

Professor, National University of Singapore
Verified email at nus.edu.sg
Cited by 13142

In vivo photodynamic therapy using upconversion nanoparticles as remote-controlled nanotransducers

NM Idris, MK Gnanasammandhan, J Zhang, PC Ho… - Nature medicine, 2012 - nature.com
Conventional photodynamic therapy (PDT) is limited by the penetration depth of visible light
needed for its activation. Here we used mesoporous-silica–coated upconversion fluorescent …

Percutaneous coronary intervention versus coronary artery bypass grafting in patients with three-vessel or left main coronary artery disease: 10-year follow-up of the …

…, H Reichenspurner, C Stark, M Laine, PC Ho… - The Lancet, 2019 - thelancet.com
Background The Synergy between PCI with Taxus and Cardiac Surgery (SYNTAX) trial was
a non-inferiority trial that compared percutaneous coronary intervention (PCI) using first-…

Comparison of iron-, nickel-, copper-and manganese-based oxygen carriers for chemical-looping combustion

P Cho, T Mattisson, A Lyngfelt - Fuel, 2004 - Elsevier
… In this work, the reaction rates are measured at 950 C for all oxygen carriers except for
tests with C6AC which were run at 850 C. The oxygen carriers were preheated in an inert …

The impact of aqueous solubility and dose on the pharmacokinetic profiles of resveratrol

S Das, HS Lin, PC Ho, KY Ng - Pharmaceutical research, 2008 - Springer
Purpose This study aimed at the investigation of the impact of aqueous solubility and dose
manipulation on the pharmacokinetics of resveratrol. Methods Water soluble intravenous and …

Noninvasive urinary metabonomic diagnosis of human bladder cancer

KK Pasikanti, K Esuvaranathan, PC Ho… - Journal of proteome …, 2010 - ACS Publications
Cystoscopy is considered the gold standard for the clinical diagnosis of human bladder cancer
(BC). As cystoscopy is expensive and invasive, it may compromise patients’ compliance …

Determination of pterostilbene in rat plasma by a simple HPLC‐UV method and its application in pre‐clinical pharmacokinetic study

HS Lin, BD Yue, PC Ho - Biomedical Chromatography, 2009 - Wiley Online Library
A simple HPLC‐UV method was developed and validated for the quantification of pterostilbene
(3,5‐dimethoxy‐4'‐hydroxy‐trans‐stilbene), a pharmacologically active phytoalexin in rat …

[HTML][HTML] Intranasal administration of carbamazepine-loaded carboxymethyl chitosan nanoparticles for drug delivery to the brain

S Liu, S Yang, PC Ho - asian journal of pharmaceutical sciences, 2018 - Elsevier
Epilepsy is considered as a common and diverse set of chronic neurological disorders and
its symptoms can be controlled by antiepileptic drugs (AEDs). The presence of p-glycoprotein …

[HTML][HTML] Ursolic acid inhibits the initiation, progression of prostate cancer and prolongs the survival of TRAMP mice by modulating pro-inflammatory pathways

MK Shanmugam, TH Ong, AP Kumar, CK Lun, PC Ho… - PloS one, 2012 - journals.plos.org
Prostate cancer is one of the leading causes of cancer death among men worldwide. In this
study, using transgenic adenocarcinoma of mouse prostate (TRAMP) mice, the effect of diet …

Ursolic acid inhibits multiple cell survival pathways leading to suppression of growth of prostate cancer xenograft in nude mice

…, S Kapoor, A Sharma, AP Kumar, PC Ho… - Journal of molecular …, 2011 - Springer
Activation of transcription factors nuclear factor-κB (NF-κB) and signal transducer and activator
of transcription 3 (STAT3) is frequently observed in prostate cancer and has been linked …

Comprehensive physicochemical, pharmacokinetic and activity profiling of anti-TB agents

SB Lakshminarayana, TB Huat, PC Ho… - Journal of …, 2015 - academic.oup.com
Objectives The discovery and development of TB drugs has met limited success, with two
new drugs approved over the last 40 years. Part of the difficulty resides in the lack of well-…