Pyrimidine ring is the building unit of DNA and RNA and thus pyrimidine based chemical
architectures exhibit diverse pharmacological activities. Among the reported medicinal …

Brönsted acid catalysts have been used in a number of organic transformations. To overcome
limitations, such as toxicity, volatility, high price and hazardous nature of the conventional …

Novel quinazolines, having interesting antibacterial activity have been prepared,
characterized and tested against a panel of susceptible and resistant Gram positive and …

Tubulin is one of the most useful and strategic molecular targets for anticancer drugs. The
dynamic process of microtubule assembly and disassembly can be blocked by various agents …

A novel series of triazole‐linked isatin‐indole‐3‐carboxaldehyde hybrids based on the
febuxostat skeleton and its binding site interactions were rationally designed and synthesized as …

Protein kinases constitute one of the largest and most functionally diverse gene families that
regulate key cell functions. In past several years, kinase inhibition has emerged as potential …

A series of 4,6‐diaryl/heteroarylpyrimidones was synthesized employing silica‐supported
fluoroboric acid under solvent‐free conditions in a microwave reactor. The catalytic influence …

Several thieno [3,2-d]pyrimidin-4-ones (4a-i) were conveniently prepared by the thio-claisen
rearrangement of 5-prop-2-ynylsulfanyl pyrimidin-4-ones derivatives. The constitution of the …

Several 1-aryl-2-phenyl-4-piperidino-4-thioalkyl-1,3-diazabuta-1,3-dienes were prepared
by the treatment of N-arylimino isothiocyanate with piperidine followed by S-alkylation with …

… Preet Mohinder Singh Bedi* Preet Mohinder Singh Bedi … Preet Mohinder Singh Bedi -
Department of Pharmaceutical Sciences, Guru Nanak Dev University, Amritsar, Punjab 143005, …