User profiles for R. Tirumalai

Madhan R Tirumalai

University of Houston, Houston, TX, USA
Verified email at central.uh.edu
Cited by 1778

[HTML][HTML] The human plasma proteome: a nonredundant list developed by combination of four separate sources

…, M Polanski, R Pieper, T Gatlin, RS Tirumalai… - Molecular & Cellular …, 2004 - ASBMB
We have merged four different views of the human plasma proteome, based on different
methodologies, into a single nonredundant list of 1175 distinct gene products. The …

[HTML][HTML] Characterization of the low molecular weight human serum proteome* s

RS Tirumalai, KC Chan, DRA Prieto, HJ Issaq… - Molecular & cellular …, 2003 - ASBMB
Serum potentially carries an archive of important histological information whose determination
could serve to improve early disease detection. The analysis of serum, however, is …

Similarities and differences among 105 members of the Int family of site-specific recombinases

SE Nunes-Düby, HJ Kwon, RS Tirumalai… - Nucleic acids …, 1998 - academic.oup.com
Alignments of 105 site-specific recombinases belonging to the Int family of proteins identified
extended areas of similarity and three types of structural differences. In addition to the …

[PDF][PDF] Peer reviewed: SELDI-TOF MS for diagnostic proteomics

HJ Issaq, TP Conrads, DRA Prieto, R Tirumalai… - 2003 - ACS Publications
… Prieto Radhakrishna Tirumalai • Timothy D. Veenstra … Radhakrishna Tirumalai is a
senior scientist whose research interests include structure–function relationships in proteins …

Flexibility in DNA recombination: structure of the lambda integrase catalytic core

HJ Kwon, R Tirumalai, A Landy, T Ellenberger - Science, 1997 - science.org
Lambda integrase is archetypic of site-specific recombinases that catalyze intermolecular
DNA rearrangements without energetic input. DNA cleavage, strand exchange, and religation …

Occurrence of vertebrate steroids, estradiol 17β and progesterone in the reproducing females of the mud crab Scylla serrata

SR Warrier, R Tirumalai, T Subramoniam - Comparative Biochemistry and …, 2001 - Elsevier
In crustaceans, vitellogenesis is known to be controlled by eyestalk neuropeptides, biogenic
amines, ecdysteroids and a juvenile hormone-like compound, methyl farnesoate. In recent …

Acrolein causes transcriptional induction of phase II genes by activation of Nrf2 in human lung type II epithelial (A549) cells

R Tirumalai, TR Kumar, KH Mai, S Biswal - Toxicology letters, 2002 - Elsevier
Acrolein, an α,β-unsaturated aldehyde, is by far the strongest electrophile present in cigarette
smoke which is involved in several lung pathophysiological conditions. Acrolein depletes …

The peptidyl transferase center: a window to the past

MR Tirumalai, M Rivas, Q Tran… - … and Molecular Biology …, 2021 - Am Soc Microbiol
In his 2001 article, “Translation: in retrospect and prospect,” the late Carl Woese made a
prescient observation that there was a need for the then-current view of translation to be “…

[HTML][HTML] The emergence of life

…, F Raulin, MJ Russell, A Spang, MR Tirumalai… - Space Science …, 2019 - Springer
The aim of this article is to provide the reader with an overview of the different possible scenarios
for the emergence of life, to critically assess them and, according to the conclusions we …

Lambda integrase cleaves DNA in cis.

SE Nunes‐Düby, RS Tirumalai, L Dorgai, E Yagil… - The EMBO …, 1994 - embopress.org
In the Int family of site‐specific recombinases, DNA cleavage is accomplished by nucleophilic
attack on the activated scissile phosphodiester bond by a specific tyrosine residue. It has …