Doxorubicin (DOX) is an antineoplastic agent clinically employed for treating breast cancer
patients. Despite its effectiveness, its inherent adverse toxic side effects often limit its clinical …

The eye is an organ with limited drug access due to its anatomical and physiological barriers,
and the usual forms of ocular administration are limited in terms of drug penetration, …

Sodium butyrate-loaded nanoparticles coated chitosan (NaBu-loaded nanoparticles/CS)
were developed to treat the choroidal neovascularization in wet age-related macular …

Purpose To verify the safety of different doses of intravitreal metoprolol tartrate (MT) after
intravitreal injection in rabbit eyes. Methods Animals were randomly assigned into 2 groups: …

Abstract Nanostructured polymer blends exhibit better properties over bulk polymeric blends
and their homopolymers since several properties, such as stability, tensile strength, ductility, …

Cleaning validation is the documented evidence that shows the effectiveness of cleaning
procedures for the removal of product residues and other contaminants. The cleaning …

Radiolabeling cidofovir with technetium-99m (99mTc-CDV) is an innovative procedure that
enables real-time monitoring of the drug. Essays were performed in vitro, showing high …

During the development of polymeric wound coating materials, the in vivo reactions play a
key role in the success of the material for tissue engineering. In this work, the chick …

Retinal vein occlusion is characterized by a thrombotic vascular obstruction and is an important
cause of blindness worldwide. The treatment of this condition is still very challenging due …

Recurrent respiratory papillomatosis (RRP) is a chronic disease caused by Human Papilloma
Virus (HPV) and affects mainly children and teenagers. Besides there is no definitive …