The disposition of poly-hexyl-2-cyanoacrylate nanoparticles in tears, aqueous humor,
cornea and conjunctiva of albino rabbits was studied using radiotracer techniques. Results …

The objective of this study was to evaluate ocular delivery of a lipid-soluble drug, [ 3 H]progesterone,
using nanoparticles. Polybutylcyanoacrylate nanoparticles loaded with [ 3 H]…

Delivery of drugs to the respiratory tract is important for both local and systemic treatment of
disease (1). With formulations intended to be delivered as aerosols, the efficiency of delivery …

The thermodynamics of encapsulation and the kinetics of efflux were studied for a series of
small molecular-weight drugs in multilamellar and unilamellar liposomes. Liposome …

This chapter provides a theoretical basis for the use of size reduction techniques to solve the
formulator's challenge with poorly water-soluble Drug Substance (API). It describes various …

Drug delivery systems that overcome drug stability problems inherent in conventional dosage
forms warrant attention. The drug would be delivered intravenously in the solution phase …

The dissolution behavior of highly soluble drugs having varying diffusion coefficients was
investigated using the rotating disk methodology. The effect of solution viscosity as a result of …

A rapid method for determining the equilibrium water vapor pressure over a hydrate or saturated
solution has been developed. The vapor space over the sample in an isothermal, heat …

Lyophilized, amorphous acadesine crystallizes when exposed to water vapor. Isothermal
calorimetry of samples held at constant humidity showed crystallization always occured within …

The most convenient and commonly employed route of drug delivery has historically been
by oral ingestion. For routes involving drug absorption, such as the oral or im route, an …