Over the past several years, great advances have been made on development of novel
drug delivery systems (NDDS) for plant actives and extracts. The variety of novel herbal …

Transdermal drug delivery system (TDDS) utilizes the skin as executable route for drug
administration but the foremost barrier against drug permeability is the stratum corneum and …

… scale to nature such as biologicals like proteins, DNA and viruses, which are of the order
of 10’s of nanometers in size and cells and cellular assemblies of the order of 1000’s of …

… Author links open overlay panel Mukta Agrawal a , Swarnlata Saraf b , Shailendra Saraf
b c , Sophia G. Antimisiaris d e , Mahavir Bhupal Chougule f g h , Sunday A. Shoyele i , Amit …

The versatile pharmaceutical material cyclodextrin’s (CDs) are classified into hydrophilic,
hydrophobic, and ionic derivatives. By the early 1950s the basic physicochemical …

… (S)-… Stransferace and quinine reductase in the liver and mucosa of the small intestine to
detoxify chemical carcinogenesis. Studies show that the activity of phase II enzyme glutathione-S…

Purpose To establish the safety profile and antitumor activity of the anti–programmed death
1 receptor monoclonal antibody, pembrolizumab, in patients with recurrent or metastatic …

… Different derivatives of N-[3,4-disubstituted-1,3-thiazol-2(3H)-ylidene]-2-(pyrazin-2-yloxy)acetohydrazide
and N-[(2)-3-(4-alkyl/aryl substituted)-4-oxo-1,3-thiazolidin-2-ylidene]-2-(pyrazin-2-yloxy)acetohydrazide …

Background : Transcatheter aortic valve replacement (TAVR) is being increasingly performed
in patients with bicuspid aortic valve stenosis (AS). Objectives : This study sought to …

Purpose The KEYNOTE-028 trial (ClinicalTrials. gov identifier: NCT02054806) was designed
to assess the safety and efficacy of pembrolizumab in 20 programmed death ligand 1–…