Impact of media and antifoam selection on monoclonal antibody production and quality using a high throughput micro‐bioreactor system
SR Velugula‐Yellela, A Williams… - Biotechnology …, 2018 - Wiley Online Library
Monoclonal antibody production in commercial scale cell culture bioprocessing requires a
thorough understanding of the engineering process and components used throughout …
thorough understanding of the engineering process and components used throughout …
Real‐time quantification and supplementation of bioreactor amino acids to prolong culture time and maintain antibody product quality
…, EJ Fratz‐Berilla, SR Velugula‐Yellela… - Biotechnology …, 2019 - Wiley Online Library
Real‐time monitoring of cell cultures in bioreactors can enable expedited responses necessary
to correct potential batch failure perturbations which may normally go undiscovered until …
to correct potential batch failure perturbations which may normally go undiscovered until …
Use of high-throughput automated microbioreactor system for production of model IgG1 in CHO cells
SR Velugula-Yellela, C Kohnhorst, DN Powers… - JoVE (Journal of …, 2018 - jove.com
Automated microscale bioreactors (15 mL) can be a useful tool for cell culture engineers.
They facilitate the simultaneous execution of a wide variety of experimental conditions while …
They facilitate the simultaneous execution of a wide variety of experimental conditions while …
Impacts on product quality attributes of monoclonal antibodies produced in CHO cell bioreactor cultures during intentional mycoplasma contamination events
…, T Faison, SR Velugula‐Yellela… - Biotechnology and …, 2020 - Wiley Online Library
A mycoplasma contamination event in a biomanufacturing facility can result in costly cleanups
and potential drug shortages. Mycoplasma may survive in mammalian cell cultures with …
and potential drug shortages. Mycoplasma may survive in mammalian cell cultures with …
Purification and analytics of a monoclonal antibody from chinese hamster ovary cells using an automated microbioreactor system
SR Velugula-Yellela, DN Powers, P Angart… - JoVE (Journal of …, 2019 - jove.com
Monoclonal antibodies (mAbs) are one of the most popular and well-characterized biological
products manufactured today. Most commonly produced using Chinese hamster ovary (…
products manufactured today. Most commonly produced using Chinese hamster ovary (…
[PDF][PDF] Bioprocess: robustness with respect to Mycoplasma Species
…, S Dolan, C Breuning, SR Velugula-Yellela… - PDA J Pharm Sci …, 2020 - academia.edu
Capture bioprocessing unit operations were previously shown to clear or kill several log10
of a model mycoplasma Acholeplasma laidlawii in lab-scale spike/removal studies. Here, we …
of a model mycoplasma Acholeplasma laidlawii in lab-scale spike/removal studies. Here, we …
Impacts of intentional mycoplasma contamination on CHO cell bioreactor cultures
…, CL Kohnhorst, SR Velugula‐Yellela… - Biotechnology and …, 2019 - Wiley Online Library
Mycoplasma contamination events in biomanufacturing facilities can result in loss of
production and costly cleanups. Mycoplasma may survive in mammalian cell cultures with only …
production and costly cleanups. Mycoplasma may survive in mammalian cell cultures with only …
Research on the Strategy of Using the All-Media Matrix to Shape and Promote” Healthy Guangzhou” Cultural Brands
M Huang, Y Xiong - 2020 International Conference on Urban …, 2020 - ieeexplore.ieee.org
Urban brands include five major elements. The communication strategy of cultural brands
strives to inform the audience of new value points and the brand image that they want to …
strives to inform the audience of new value points and the brand image that they want to …
[CITATION][C] Automated Microbioreactors and the Characterization of Media Dependent Changes in Antibody Product Glycosylation and Aglycosylation
DN Powers, SR Velugula-Yellela, N Trunfio, P Angart… - J Glycobiol, 2018