A new standard has been developed by the International Organization for Standardization (ISO)
for evaluating contact lens disinfectants. This paper reviews the ISO 14729 standard …

The antimicrobial effectiveness test first appeared as a USP General Chapter in the 18th
revision, official September 1, 1970. This chapter, at the beginning, was designed to evaluate …

The sterility test is generally recognized as a flawed test for its stated purpose. Since the
original description in 1932. this test has generated controversy as to its role in product quality …

We evaluated the efficacy of different neutralizing solutions for use in disinfectant efficacy
assays. Our approach used comparisons between the recoveries of low inocula in different …

The study of biocidal efficacy requires a distinction between the potential forms of antimicrobial
effects. An antimicrobial agent can be either biocidal or biostatic. A disinfectant or …

This article is a comprehensive review of the published activities of the Microbiology
Subcommittee of the USP Committee of Revision for the 1995-2000 revision cycle. The activities of …

Cosmetics do not need to be sterile, but they must be adequately preserved or protected
from microbial contamination and spoilage. When consumers use cosmetic products, they …

The Multi-item Microbial Challenge Test (MIMCT) is a stringent, carrier assay of the
disinfecting efficacy of a contact lens care regimen. The test involves four steps: 1) in vitro …

The adequate neutralization of contact lens solutions is essential in all aspects of microbiological
testing of preserved, and disinfecting, solutions. Four commonly employed tests are …

Cosmetics do not need to be sterile, but they must be adequately preserved. When consumers
use cosmetic products, they repeatedly challenge the cosmetic with microorganisms in …