[HTML][HTML] Individualized, heterologous chimpanzee adenovirus and self-amplifying mRNA neoantigen vaccine for advanced metastatic solid tumors: phase 1 trial …

…, G Grotenbreg, R Greer, W Blair, MD Cao, S Chan… - Nature medicine, 2022 - nature.com
Checkpoint inhibitor (CPI) therapies provide limited benefit to patients with tumors of low
immune reactivity. T cell-inducing vaccines hold promise to exert long-lasting disease control in …

MIT CAACB Risk Assessment Case Study: Assessing virus cross-contamination risk between two simultaneous processes in an open biomanufacturing facility

…, J Leung, ME Wiebe, MT Brewer, S Chan… - PDA Journal of …, 2023 - journal.pda.org
Some members of MIT's Consortium on Adventitious Agent Contamination in Biomanufacturing
(CAACB) previously published content on the “Quality Risk Management in the Context …

Tax Risk, Corporate Governance, and the Valuation of Tax Avoidance Across Philippine Firms: How Do Investors Value Corporate Tax Avoidance?

CE Ang, SLS Chan, SEG Sow, SK Yap, MB Estabillo… - 2022 - animorepository.dlsu.edu.ph
Tax avoidance has traditionally been thought to enhance firm value because it generates
cash savings for reinvestment or distribution to shareholders. More recent literature, however, …

Analysing the effect of CSF inflammatory proteins on stroke severity in people with varying severities of Alzheimer's disease

SKZ Chan - 2023 - dr.ntu.edu.sg
Stroke is a debilitating condition that affects ~25% of the world’s population with many risk
factors such as Alzheimer’s Disease (AD). In stroke, inflammatory responses contribute to …

Corporate governance, firm size, and tax avoidance: How does corporate governance influence tax avoidance across small and large Philippine firms?

CE Ang, SLS Chan, SEG Sow, SK Yap - 2023 - animorepository.dlsu.edu.ph
Corporate taxes represent costs that are proportional to an entity’s profit, which could substantially
impact a firm’s financial bottom line. To improve profitability, many firms have turned to …

Normalization of obesity-associated insulin resistance through immunotherapy

S Winer, Y Chan, G Paltser, D Truong, H Tsui… - Nature medicine, 2009 - nature.com
Obesity and its associated metabolic syndromes represent a growing global challenge, yet
mechanistic understanding of this pathology and current therapeutics are unsatisfactory. We …

[HTML][HTML] Detection of air and surface contamination by SARS-CoV-2 in hospital rooms of infected patients

…, T Barkham, PP De, S Vasoo, M Chan… - Nature …, 2020 - nature.com
Understanding the particle size distribution in the air and patterns of environmental contamination
of SARS-CoV-2 is essential for infection prevention policies. Here we screen surface …

An active diagnostic system for structural health monitoring of rocket engines

XP Qing, HL Chan, SJ Beard… - Journal of intelligent …, 2006 - journals.sagepub.com
An active diagnostic system using built-in piezoelectric actuator/sensor networks was developed
for monitoring crack growth in a rocket engine pipe. The diagnostic system combines a …

Epidemiological and clinical predictors of COVID-19

…, OT Ng, B Young, S Vasoo, M Chan… - Clinical Infectious …, 2020 - academic.oup.com
Background Rapid identification of COVID-19 cases, which is crucial to outbreak containment
efforts, is challenging due to the lack of pathognomonic symptoms and in settings with …

Validation of the social functioning scale: Comparison and evaluation in early psychosis, autism spectrum disorder and social anxiety disorder

EHC Chan, SDX Kong, SH Park, YJC Song… - Psychiatry …, 2019 - Elsevier
Social functioning is an important component of mental disorders for assessment and
treatment. There is no recognised self-report instrument to measure social functioning across …