We report 80,388 ESTs from 23 Atlantic salmon (Salmo salar) cDNA libraries (61,819 ESTs),
6 rainbow trout (Oncorhynchus mykiss) cDNA libraries (14,544 ESTs), 2 chinook salmon (…

Among mammals, genetic recombination occurs at highly delimited sites known as recombination
hotspots. They are typically 1–2 kb long and vary as much as a 1,000-fold or more in …

A physical map of the Atlantic salmon (Salmo salar) genome was generated based on HindIII
fingerprints of a publicly available BAC (bacterial artificial chromosome) library constructed …

High-throughput sequencing (HTS) is capable of broad virus detection encompassing both
known and unknown adventitious viruses in a variety of sample matrices. We describe the …

Background Unbiased deep sequencing offers the potential for improved adventitious virus
screening in vaccines and biotherapeutics. Successful implementation of such assays will …

Next-generation sequencing (NGS) has been proven to address some of the limitations of
the current testing methods for adventitious virus detection in biologics. The International …

Transcriptional regulators encoded by the Myocyte Enhancer Factor 2 (MEF2) gene family
play a fundamental role in cardiac development, homeostasis and pathology. Previous …

There is a need for a broad and efficient testing strategy for the detection of both known and
novel viral adventitious agents in vaccines and biologicals. High-throughput sequencing (…

The capability of high-throughput sequencing (HTS) for detection of known and unknown
viruses makes it a powerful tool for broad microbial investigations, such as evaluation of novel …

Several nucleic-acid based technologies have recently emerged with capabilities for broad
virus detection. One of these, high throughput sequencing, has the potential for novel virus …