Purpose To predict the crystallization time of amorphous solid dispersions by controlling the
combined effect of temperature and moisture content. Methods The authors exposed …

Neoplastic pancreatic epithelial cells are believed to die through caspase 8-dependent
apoptotic cell death, and chemotherapy is thought to promote tumour apoptosis 1 . Conversely, …

Pancreatic ductal adenocarcinoma is an aggressive cancer that interacts with stromal cells
to produce a highly inflammatory tumor microenvironment that promotes tumor growth and …

Nonalcoholic steatohepatitis (NASH) is the most common etiology of chronic liver dysfunction
in the United States and can progress to cirrhosis and liver failure. Inflammatory insult …

Modulation of Toll-like receptor (TLR) signaling can have protective or protumorigenic effects
on oncogenesis depending on the cancer subtype and on specific inflammatory elements …

Dendritic cells (DC) are professional APCs that regulate innate and adaptive immunity. The
role of fatty-acid synthesis in DC development and function is uncertain. We found that …

Dectin-1 is a C-type lectin receptor critical in anti-fungal immunity, but Dectin-1 has not been
linked to regulation of sterile inflammation or oncogenesis. We found that Dectin-1 …

Background & Aims Subsets of leukocytes synergize with regenerative growth factors to promote
hepatic regeneration. γδT cells are early responders to inflammation-induced injury in a …

Cancer cachexia is a debilitating condition characterized by a combination of anorexia, muscle
wasting, weight loss, and malnutrition. This condition affects an overwhelming majority of …

Con A hepatitis is regarded as a T cell–mediated model of acute liver injury. Mincle is a C-type
lectin receptor that is critical in the immune response to mycobacteria and fungi but does …