[HTML][HTML] Efficacy and safety of ornithine phenylacetate for treating overt hepatic encephalopathy in a randomized trial
…, N Pyrsopoulos, A Potthoff, S Bukofzer… - Clinical …, 2021 - Elsevier
Background & Aims Hepatic encephalopathy (HE) is associated with increased morbidity,
mortality, and healthcare resource use. In this phase 2b study, we evaluated the efficacy and …
mortality, and healthcare resource use. In this phase 2b study, we evaluated the efficacy and …
Industry perspective on the medical risk of visible particles in injectable drug products
S Bukofzer, J Ayres, A Chavez, M Devera… - PDA Journal of …, 2015 - journal.pda.org
Sterile injectable products are used extensively in health care. Patients, caregivers,
manufacturers, and regulators have an inherent expectation for safe and effective injectable drug …
manufacturers, and regulators have an inherent expectation for safe and effective injectable drug …
Comparison of hepatitis B virus DNA extractions from serum by the QIAamp blood kit, GeneReleaser, and the phenol-chloroform method
A Kramvis, S Bukofzer, MC Kew - Journal of Clinical Microbiology, 1996 - Am Soc Microbiol
The abilities of GeneReleaser and QIAamp to extract the hepatitis B virus (HBV) DNA
template from serum for amplification by PCR were evaluated and compared with that of the …
template from serum for amplification by PCR were evaluated and compared with that of the …
A randomized, double-blind, placebo-controlled study assessing the safety and tolerability of regadenoson in subjects with asthma or chronic obstructive pulmonary …
BM Prenner, S Bukofzer, S Behm, K Feaheny… - Journal of Nuclear …, 2012 - Elsevier
Background Adenosine receptor stress agents for myocardial perfusion imaging (MPI) may
cause A 2B and/or A 3 receptor-mediated bronchoconstriction, of particular concern to …
cause A 2B and/or A 3 receptor-mediated bronchoconstriction, of particular concern to …
Double–blind, crossover comparison of 3 mg apomorphine SL with placebo and with 4 mg apomorphine SL in male erectile dysfunction
E Dula, S Bukofzer, R Perdok, M George - European urology, 2001 - karger.com
Objective: To establish the efficacy and safety of a fixed, 3–mg dose of apomorphine SL
compared with placebo, and to compare 3 mg with 4 mg apomorphine SL in patients with …
compared with placebo, and to compare 3 mg with 4 mg apomorphine SL in patients with …
Safety, tolerability, and pharmacokinetics of l‐ornithine phenylacetate in patients with acute liver injury/failure and hyperammonemia
…, D Ganger, RM Subramanian, S Bukofzer… - Hepatology, 2018 - journals.lww.com
Notch signaling plays an emerging role in the regulation of immune cell development and
function during inflammatory response. Activation of the ras homolog gene family member A/…
function during inflammatory response. Activation of the ras homolog gene family member A/…
[PDF][PDF] Microarray analysis in human hepatocytes suggests a mechanism for hepatotoxicity induced by trovafloxacin
MJ Liguori, MG Anderson, S Bukofzer, J McKim… - …, 2005 - Wiley Online Library
Idiosyncratic drug toxicity, defined as toxicity that is dose independent, host dependent, and
usually cannot be predicted during preclinical or early phases of clinical trials, is a …
usually cannot be predicted during preclinical or early phases of clinical trials, is a …
Hepatitis B virus precore mutants in serum and liver of Southern African Blacks with hepatocellular carcinoma
A Kramvis, MC Kew, S Bukofzer - Journal of hepatology, 1998 - Elsevier
Background/Aim: The aim of this study was to sequence the precore region of HBV isolated
from serum and tumorous and non-tumorous liver tissue from patients with hepatocellular …
from serum and tumorous and non-tumorous liver tissue from patients with hepatocellular …
The role of membranous obstruction of the inferior vena cava in the etiology of hepatocellular carcinoma in Southern African blacks
MC Kew, A McKnight, J Hodkinson, S Bukofzer… - Hepatology, 1989 - journals.lww.com
Membranous obstruction of the inferior vena cava has been incriminated as a risk factor for
hepatocellular carcinoma in South African Blacks and in Japanese. However, the frequency …
hepatocellular carcinoma in South African Blacks and in Japanese. However, the frequency …
[HTML][HTML] Effect of caffeine on SPECT myocardial perfusion imaging during regadenoson pharmacologic stress: a prospective, randomized, multicenter study
…, RC Thompson, R Kristy, S Bukofzer - The international journal of …, 2014 - Springer
A multicenter, double-blind, randomized study was conducted to assess the effect of caffeine
on regadenoson stress myocardial perfusion imaging (MPI). Subjects with a high likelihood …
on regadenoson stress myocardial perfusion imaging (MPI). Subjects with a high likelihood …