We sequenced the 29,751-base genome of the severe acute respiratory syndrome (SARS)–associated
coronavirus known as the Tor2 isolate. The genome sequence reveals that this …

We report the draft genome of the black cottonwood tree, Populus trichocarpa. Integration of
shotgun sequence assembly with genetic mapping enabled chromosome-scale …

We created a visualization tool called Circos to facilitate the identification and analysis of
similarities and differences arising from comparisons of genomes. Our tool is effective in …

The reference human genome sequence set the stage for studies of genetic variation and
its association with human disease, but epigenomic studies lack a similar reference. To …

For a decade, The Cancer Genome Atlas (TCGA) program collected clinicopathologic
annotation data along with multi-platform molecular profiles of more than 11,000 human tumors …

Genetic alterations in signaling pathways that control cell-cycle progression, apoptosis, and
cell growth are common hallmarks of cancer, but the extent, mechanisms, and co-…

Widespread adoption of massively parallel deoxyribonucleic acid (DNA) sequencing
instruments has prompted the recent development of de novo short read assembly algorithms. A …

We conducted comprehensive integrative molecular analyses of the complete set of tumors
in The Cancer Genome Atlas (TCGA), consisting of approximately 10,000 specimens and …

We describe the landscape of genomic alterations in cutaneous melanomas through DNA,
RNA, and protein-based analysis of 333 primary and/or metastatic melanomas from 331 …

There is substantial heterogeneity among primary prostate cancers, evident in the spectrum
of molecular abnormalities and its variable clinical course. As part of The Cancer Genome …