Effect of terminal sterilization by irradiation on amber Type I and Type III glass containers containing veterinary oxytetracycline suspension
…, P Papadopoulos, C Rebbeck, S Schwabe… - PDA Journal of …, 2004 - journal.pda.org
The purpose of this study is to determine the effect of terminal sterilization by gamma
irradiation on 500-mL amber Type I and Type III glass containers (bottles) containing …
irradiation on 500-mL amber Type I and Type III glass containers (bottles) containing …
Contrasting phenotypes in resistance to thyroid hormone alpha correlate with divergent properties of thyroid hormone receptor α1 mutant proteins
Background: Resistance to thyroid hormone alpha (RTHα), a disorder characterized by
tissue-selective hypothyroidism and near-normal thyroid function tests due to thyroid receptor …
tissue-selective hypothyroidism and near-normal thyroid function tests due to thyroid receptor …
RNA interference therapy targeting apolipoprotein C-III in hypertriglyceridemia
…, P Clifton, D Sullivan, J Baker, C Schwabe… - NEJM …, 2023 - evidence.nejm.org
Background Apolipoprotein C-III (APOC3) inhibits triglyceride clearance by reducing lipoprotein
lipase–mediated hydrolysis and hepatocyte uptake of triglyceride-rich lipoproteins. ARO-…
lipase–mediated hydrolysis and hepatocyte uptake of triglyceride-rich lipoproteins. ARO-…
ARO-APOC3, an investigational RNAi therapeutic, shows similar efficacy and safety in genetically confirmed FCS and non-FCS participants with severe …
P Clifton, D Sullivan, J Baker, C Schwabe… - Circulation, 2021 - Am Heart Assoc
Background: Familial chylomicronemia syndrome (FCS) is an ultrarare condition caused by
biallelic pathogenic DNA variants in lipolysis-associated genes, resulting in severe …
biallelic pathogenic DNA variants in lipolysis-associated genes, resulting in severe …
Pharmacodynamic effect of ARO-APOC3, an investigational hepatocyte-targeted RNA interference therapeutic targeting apolipoprotein C3, in patients with …
P Clifton, D Sullivan, J Baker, C Schwabe… - Circulation, 2020 - Am Heart Assoc
Background: Hypertriglyceridemia (HTG) increases the risk of acute pancreatitis and
atherosclerosis. In a Phase 1 study (NCT03783377), single subcutaneous doses of investigational …
atherosclerosis. In a Phase 1 study (NCT03783377), single subcutaneous doses of investigational …
Anti-human TREM2 induces microglia proliferation and reduces pathology in an Alzheimer's disease model
…, H Rhinn, I Tassi, A Rosenthal, T Schwabe… - Journal of Experimental …, 2020 - rupress.org
TREM2 is a receptor for lipids expressed in microglia. The R47H variant of human TREM2
impairs ligand binding and increases Alzheimer’s disease (AD) risk. In mouse models of …
impairs ligand binding and increases Alzheimer’s disease (AD) risk. In mouse models of …
[BOOK][B] Specification and verification of communication protocols in AFFIRM using state transition models
…, CA Sunshine, RW Erickson, SL Gerhart, D Schwabe - 1980 - apps.dtic.mil
It is becoming increasingly important that communication protocols be formally specified
and verified. This report describes a particular approach--the state transition model--using a …
and verified. This report describes a particular approach--the state transition model--using a …
A Novel Approach for Analyzing Gene Expression Profiles Defines Two Distinct Subgroups of t (4; 11) Positive Infant Acute Lymphoblastic Leukemia Patients.
RW Stam, S Bohlander, R Kirschner-Schwabe… - 2007 - ashpublications.org
Gene expression profiles (GEPs) are becoming increasingly more important for diagnostic
procedures, allowing clinical predictions including treatment response and outcome for …
procedures, allowing clinical predictions including treatment response and outcome for …
Viscaria Alba*: En. German catchfly, Clammy campion; Ge., Klebnelke
S Taylor, WW Schwabe - Handbook of Flowering, 2019 - taylorfrancis.com
Visearía alba is a member of the Caryophyllaceae and is commonly grown as a herbaceous
garden ornamental. The species is perennial, with erect and densely leafy and short shoots …
garden ornamental. The species is perennial, with erect and densely leafy and short shoots …
[PDF][PDF] Propositional arguments in English, German, Hungarian, Italian and Polish
…, L Gunkel, S Schlotthauer, K Schwabe… - Book of …, 2023 - ids-pub.bsz-bw.de
In many European languages, propositional arguments (PAs) can be realized as different
types of structures. Cross-linguistically, complex structures with PAs show a systematic …
types of structures. Cross-linguistically, complex structures with PAs show a systematic …