Lipases for biotechnology

KE Jaeger, T Eggert - Current opinion in biotechnology, 2002 - Elsevier
Lipases constitute the most important group of biocatalysts for biotechnological applications.
The high-level production of microbial lipases requires not only the efficient overexpression …

Enantioselective biocatalysis optimized by directed evolution

KE Jaeger, T Eggert - Current opinion in biotechnology, 2004 - Elsevier
Directed evolution methods are now widely used for the optimization of diverse enzyme
properties, which include biotechnologically relevant characteristics like stability, regioselectivity …

Eye movement recordings: methods

T Eggert - Neuro-Ophthalmology, 2007 - karger.com
The development of oculomotor research is closely related to the development of the
technology of eye movement recordings. The first part of this chapter summarizes some …

STAR detector overview

…, V Eckardt, WR Edwards, LG Efimov, T Eggert… - Nuclear Instruments and …, 2003 - Elsevier
… Inclusive p t and η distributions of charged particles will be measured in STAR to investigate
the degree of thermalization, contribution of collective flow, possible effects of disoriented chiral …

Elliptic Flow in Collisions at

…, V Eckardt, WR Edwards, LG Efimov, T Eggert… - Physical Review Letters, 2001 - APS
Elliptic flow from nuclear collisions is a hadronic observable sensitive to the early stages of
system evolution. We report first results on elliptic flow of charged particles at midrapidity in Au…

Extractables characterization for five materials of construction representative of packaging systems used for parenteral and ophthalmic drug products

D Jenke, J Castner, T Egert, T Feinberg… - PDA Journal of …, 2013 - journal.pda.org
Polymeric and elastomeric materials are commonly encountered in medical devices and
packaging systems used to manufacture, store, deliver, and/or administer drug products. …

[HTML][HTML] Distinct functions of senescence-associated immune responses in liver tumor surveillance and tumor progression

T Eggert, K Wolter, J Ji, C Ma, T Yevsa, S Klotz… - Cancer cell, 2016 - cell.com
Oncogene-induced senescence causes hepatocytes to secrete cytokines, which induce
their immune-mediated clearance to prevent tumor initiation, a process termed "senescence …

Reporter proteins for in vivo fluorescence without oxygen

T Drepper, T Eggert, F Circolone, A Heck… - Nature …, 2007 - nature.com
Fluorescent reporter proteins such as green fluorescent protein are valuable noninvasive
molecular tools for in vivo real-time imaging of living specimens. However, their use is …

NAFLD causes selective CD4+ T lymphocyte loss and promotes hepatocarcinogenesis

C Ma, AH Kesarwala, T Eggert, J Medina-Echeverz… - Nature, 2016 - nature.com
… CD8 + T lymphocytes, leading to accelerated hepatocarcinogenesis. We also demonstrate
that CD4 + T lymphocytes have greater mitochondrial mass than CD8 + T lymphocytes and …

Systematic screening of all signal peptides from Bacillus subtilis: a powerful strategy in optimizing heterologous protein secretion in Gram-positive bacteria

…, R Freudl, A Jockwer, T Noll, T Eggert - Journal of molecular …, 2006 - Elsevier
Efficient protein secretion is very important in biotechnology as it provides active and stable
enzymes, which are an essential prerequisite for successful biocatalysis. Therefore, …