Recombinant protein therapeutics, vaccines, and plasma products have a long record of
safety. However, the use of cell culture to produce recombinant proteins is still susceptible to …

Mammalian cells are the expression system of choice for therapeutic proteins, especially those
requiring complex post‐translational modifications. Traditionally, these cells are grown in …

Since the emergence of SARS-CoV-2 numerous antibody assays have become available,
demonstrating different performance characteristics. This study focused on a quantitative …

Background In recent months numerous health care professional acquired COVID-19 at the
workplace resulting in significant shortages in medical and nursing staff. We investigated …

This article reviews currently available scientific literature related to the epidemiology,
infectivity, survival, and susceptibility to disinfectants of Coronaviruses, in the context of the …

BACKGROUND: Solvent/detergent (S/D) treatment is an established virus inactivation
technology that has been applied in the manufacture of medicinal products derived from human …

Biopharmaceuticals are of increasing importance in the treatment of a variety of diseases. A
remaining concern associated with their production is the potential introduction of …

After vaccination of humans with tick-borne encephalitis virus (TBEV) vaccine, the extent of
cross-neutralization between viruses of the European, Far Eastern, and Siberian subtypes of …

Antibody-dependent enhancement of flavivirus infection, which except for dengue virus is
without clear proof in vivo, is still under debate. Recently, postexposure immunoglobulin …

The 2020 SARS-CoV-2 pandemic is caused by a zoonotic coronavirus transmitted to humans,
similar to earlier events. Whether the other, seasonally circulating coronaviruses induce …